CNS penetration of potential anti-COVID-19 drugs.

Richardson, Peter J; Ottaviani, Silvia; Prelle, Alessandro; Stebbing, Justin; Casalini, Giacomo; Corbellino, Mario

Richardson, Peter J; Ottaviani, Silvia; Prelle, Alessandro; Stebbing, Justin; Casalini, Giacomo; Corbellino, Mario.

Richardson PJ; BenevolentAI, London, UK.
Ottaviani S; Department of Surgery and Cancer, Imperial College, London, W12 0NN, UK. silvia.ottaviani07@imperial.ac.uk.
Prelle A; Department of Neurology and Stroke Unit, ASST Ovest Milanese, Milan, Italy.
Stebbing J; Department of Surgery and Cancer, Imperial College, London, W12 0NN, UK.
Casalini G; III Division of Infectious Diseases, ASST Fatebenefratelli-Sacco, Milan, Italy.
Corbellino M; III Division of Infectious Diseases, ASST Fatebenefratelli-Sacco, Milan, Italy.

J Neurol ; 267(7): 1880-1882, 2020 Jul.

Article in English | MEDLINE | ID: covidwho-154813

Subject(s)

Betacoronavirus; Brain/metabolism; Coronavirus Infections/drug therapy; Coronavirus Infections/metabolism; Pneumonia, Viral/drug therapy; Pneumonia, Viral/metabolism; Animals; Azetidines/metabolism; Azetidines/pharmacology; Azetidines/therapeutic use; Blood-Brain Barrier/drug effects; Blood-Brain Barrier/metabolism; Brain/drug effects; COVID-19; Central Nervous System/drug effects; Central Nervous System/metabolism; Humans; Hydroxychloroquine/metabolism; Hydroxychloroquine/pharmacology; Hydroxychloroquine/therapeutic use; Pandemics; Purines; Pyrazoles; SARS-CoV-2; Sulfonamides/metabolism; Sulfonamides/pharmacology; Sulfonamides/therapeutic use

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Brain / Coronavirus Infections / Betacoronavirus Limits: Animals / Humans Language: English Journal: J Neurol Year: 2020 Document Type: Article Affiliation country: S00415-020-09866-5

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