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Advanced Pulmonary and Cardiac Support of COVID-19 Patients: Emerging Recommendations From ASAIO-A "Living Working Document".
Rajagopal, Keshava; Keller, Steven P; Akkanti, Bindu; Bime, Christian; Loyalka, Pranav; Cheema, Faisal H; Zwischenberger, Joseph B; El Banayosy, Aly; Pappalardo, Federico; Slaughter, Mark S; Slepian, Marvin J.
  • Rajagopal K; From the Departments of Clinical and Biomedical Sciences, University of Houston College of Medicine, Houston, TX.
  • Keller SP; Houston Heart, HCA Houston Healthcare, Houston, TX.
  • Akkanti B; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA.
  • Bime C; Division of Pulmonary and Critical Care Medicine, Department of Medicine, McGovern Medical School, University of Texas-Houston, Houston, TX.
  • Loyalka P; Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Arizona College of Medicine - Tucson and Banner Health, Tucson, AZ.
  • Cheema FH; Houston Heart, HCA Houston Healthcare, Houston, TX.
  • Zwischenberger JB; From the Departments of Clinical and Biomedical Sciences, University of Houston College of Medicine, Houston, TX.
  • El Banayosy A; Houston Heart, HCA Houston Healthcare, Houston, TX.
  • Pappalardo F; HCA Research Institute, Nashville, TN.
  • Slaughter MS; Department of Surgery, University of Kentucky College of Medicine and Medical Center, Lexington, KY.
  • Slepian MJ; Nazih Zuhdi Transplant Institute, Integris Baptist Medical Center, Oklahoma City, OK.
ASAIO J ; 66(6): 588-598, 2020 06.
Article in English | MEDLINE | ID: covidwho-154995
ABSTRACT
The severe acute respiratory syndrome (SARS)-CoV-2 is an emerging viral pathogen responsible for the global coronavirus disease 2019 (COVID)-19 pandemic resulting in significant human morbidity and mortality. Based on preliminary clinical reports, hypoxic respiratory failure complicated by acute respiratory distress syndrome is the leading cause of death. Further, septic shock, late-onset cardiac dysfunction, and multiorgan system failure are also described as contributors to overall mortality. Although extracorporeal membrane oxygenation and other modalities of mechanical cardiopulmonary support are increasingly being utilized in the treatment of respiratory and circulatory failure refractory to conventional management, their role and efficacy as support modalities in the present pandemic are unclear. We review the rapidly changing epidemiology, pathophysiology, emerging therapy, and clinical outcomes of COVID-19; and based on these data and previous experience with artificial cardiopulmonary support strategies, particularly in the setting of infectious diseases, provide consensus recommendations from ASAIO. Of note, this is a "living document," which will be updated periodically, as additional information and understanding emerges.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Respiratory Insufficiency / Coronavirus Infections / Betacoronavirus / Heart Diseases Type of study: Prognostic study Limits: Animals / Humans Language: English Journal: ASAIO J Journal subject: Transplantation Year: 2020 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Respiratory Insufficiency / Coronavirus Infections / Betacoronavirus / Heart Diseases Type of study: Prognostic study Limits: Animals / Humans Language: English Journal: ASAIO J Journal subject: Transplantation Year: 2020 Document Type: Article