Clinical effects of the enhanced external counterpulsation therapy in patients with ischemic chronic heart failure exacerbation COVID-19
European Heart Journal
; 42(SUPPL 1):928, 2021.
Article
in English
| EMBASE | ID: covidwho-1554603
ABSTRACT
Objectives:
The aim of the study was to assess the effects of the enhanced external counterpulsation (EECP) therapy as a rehabilitation method in patients with ischemic chronic heart failure (CHF) after COVID- 19.Methods:
54 (n=54) stable symptomatic CHF (NYHA, functional class I-II;35%≤LVEF≤50%) subjects (44 male and 10 female;mean age 61±9,8) with prior anamnesis of CAD, at least one myocardial infarction got the exacerbation of CHF after COVID-19 episode. They were randomized in a 21 manner into either 35 1-hour 250-300 mm Hg sessions of EECP (n=36;30 male, 6 female) or Sham-EECP (n=18;14 male, 4 female). All subjects had been received optimal CHF and CAD drug therapy. At baseline, a month and half a year after EECP course every subject was examined with echocardiography and 6-minute walk test.Results:
All 36 active EECP treatment group subjects improved by at least 1 NYHA class, 66% of them had no heart failure symptoms post treatment (p<0.01). 84% of treatment group pts. had sustained NYHA class improvement at half a year follow-up (p<0.01), compared with baseline. There was significant difference between LVEF 44±6,5% at baseline vs post-EECP LVEF 50±4,6% (p<0.01) in active EECP treatment group subjects. At the same time there were no significant changes of NYHA class and LVEF in Sham-EECP subjects. No one subject dies after half a year of follow up.Conclusions:
Enhanced external counterpulsation (EECP) therapy sustainably improves NYHA functional class and LVEF in patients with ischemic CHF exacerbation after COVID-19.
adult; anamnesis; conference,; controlled, study; coronavirus, disease, 2019; counterpulsation; disease, exacerbation; echocardiography; female; follow, up; heart, failure; heart, infarction; heart, left, ventricle, ejection, fraction; human; major, clinical, study; male; middle, aged; New, York, Heart, Association, class; randomized, controlled, trial; rehabilitation; six, minute, walk, test
Full text:
Available
Collection:
Databases of international organizations
Database:
EMBASE
Type of study:
Experimental Studies
/
Prognostic study
Language:
English
Journal:
European Heart Journal
Year:
2021
Document Type:
Article
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