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Prognosis of patients hospitalized with a diagnosis of COVID-19 pneumonia in a tertiary hospital in Turkey.
Birtay, Tayfun; Bahadir, Suzan; Kabacaoglu, Ebru; Yetiz, Ozgur; Demirci, Mehmet Fatih; Genctoy, Gultekin.
  • Birtay T; From the Department of Anesthesia, Baskent University, Antalya, Turkey.
  • Bahadir S; From the Department of Anesthesia, Baskent University, Antalya, Turkey.
  • Kabacaoglu E; From the Department of Chest Diseases, Baskent University, Antalya, Turkey.
  • Yetiz O; From the Department of Anesthesia, Baskent University, Antalya, Turkey.
  • Demirci MF; From the Department of Anesthesia, Baskent University, Antalya, Turkey.
  • Genctoy G; From the Department of Nephrology, Baskent University, Antalya, Turkey.
Ann Saudi Med ; 41(6): 327-335, 2021.
Article in English | MEDLINE | ID: covidwho-1555174
ABSTRACT

BACKGROUND:

SARS-CoV2/COVID-19 emerged in China and caused a global pandemic in 2020. The mortality rate has been reported to be between 0% and 14.6% in all patients. In this study, we determined the clinical and laboratory parameters of COVID-19 related morbidity and mortality in our hospital.

OBJECTIVES:

Investigate the relationship between demographic, clinical, and laboratory parameters on COVID-19-related morbidity and mortality.

DESIGN:

Retrospective observational study. SETTINGS Tertiary care hospital. PATIENTS AND

METHODS:

Patients diagnosed with COVID-19 pneumonia from March until the end of December were included in the study. MAIN OUTCOME

MEASURES:

The relationship between demographic, clinical, and laboratory parameters and the morbidity and mortality rates of patients diagnosed with COVID-19. SAMPLE SIZE 124 patients

RESULTS:

The mortality rate was 9.6% (12/124). Coronary artery disease (P<.0001) diabetes mellitus (P=.04) fever (>38.3°C) at presentation (P=.04) hypertension (P<.0001), and positive smoking history (P<.0001) were significantly associated with mortality. Patients who died were older, had a higher comorbid disease index, pneumonia severity index, fasting blood glucose, baseline serum creatinine, D-dimer, and had lower baseline haemoglobin, SaO2, percentage of lymphocyte counts and diastolic blood pressure. Patients admitted to the ICU were older, had a higher comorbidity disease index, pneumonia severity index, C-reactive protein, WBC, D-dimer, creatinine, number of antibiotics used, longer O2 support duration, lower hemoglobin, lymphocyte (%), and baseline SaO2 (%).

CONCLUSIONS:

Our results were consistent with much of the reported data. We suggest that the frequency, dosage, and duration of steroid treatment should be limited.

LIMITATIONS:

Low patient number, uncertain reason of mortality, no standard treatment regimen, limited treatment options, like ECMO. CONFLICT OF INTEREST None.
Subject(s)

Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia / COVID-19 Type of study: Diagnostic study / Observational study / Prognostic study Topics: Long Covid Limits: Humans Country/Region as subject: Asia Language: English Journal: Ann Saudi Med Journal subject: Medicine Year: 2021 Document Type: Article Affiliation country: 0256-4947.2021.327

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia / COVID-19 Type of study: Diagnostic study / Observational study / Prognostic study Topics: Long Covid Limits: Humans Country/Region as subject: Asia Language: English Journal: Ann Saudi Med Journal subject: Medicine Year: 2021 Document Type: Article Affiliation country: 0256-4947.2021.327