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Robust induction of neutralizing antibodies against the SARS-CoV-2 Delta variant after homologous Spikevax or heterologous Vaxzevria-Spikevax vaccination.
Hammerschmidt, Swantje I; Thurm, Christoph; Bosnjak, Berislav; Bernhardt, Günter; Reinhold, Annegret; Willenzon, Stefanie; Ritter, Christiane; Reinhold, Dirk; Schraven, Burkhart; Förster, Reinhold.
  • Hammerschmidt SI; Hannover Medical School, Institute of Immunology, Hannover, Germany.
  • Thurm C; Institute of Molecular and Clinical Immunology, Otto-von-Guericke-University Magdeburg, Magdeburg, Germany.
  • Bosnjak B; Research Center CHAMP (Center for Health And Medical Prevention), Otto-von-Guericke-University Magdeburg, Magdeburg, Germany.
  • Bernhardt G; Health Campus Immunology, Infectiology and Inflammation (GC-I3), Medical Faculty, Otto-von-Guericke-University Magdeburg, Magdeburg, Germany.
  • Reinhold A; Hannover Medical School, Institute of Immunology, Hannover, Germany.
  • Willenzon S; Hannover Medical School, Institute of Immunology, Hannover, Germany.
  • Ritter C; Institute of Molecular and Clinical Immunology, Otto-von-Guericke-University Magdeburg, Magdeburg, Germany.
  • Reinhold D; Research Center CHAMP (Center for Health And Medical Prevention), Otto-von-Guericke-University Magdeburg, Magdeburg, Germany.
  • Schraven B; Health Campus Immunology, Infectiology and Inflammation (GC-I3), Medical Faculty, Otto-von-Guericke-University Magdeburg, Magdeburg, Germany.
  • Förster R; Hannover Medical School, Institute of Immunology, Hannover, Germany.
Eur J Immunol ; 52(2): 356-359, 2022 02.
Article in English | MEDLINE | ID: covidwho-1555488
ABSTRACT
Sera of vaccines were assessed by surrogate virus neutralization tests for their capacity to neutralize the SARS-CoV-2 Delta variant. Homologous prime-boost immunization with Moderna's Spikevax as well as heterologous immunization with AstraZeneca's Vaxzevria followed by Moderna's Spikevax were identified as highly potent vaccination regimens for the induction of Delta-neutralizing antibodies.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Vaccination / Antibodies, Neutralizing / COVID-19 Vaccines / SARS-CoV-2 / COVID-19 / Antibodies, Viral Topics: Vaccines / Variants Limits: Female / Humans / Male Language: English Journal: Eur J Immunol Year: 2022 Document Type: Article Affiliation country: Eji.202149645

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Vaccination / Antibodies, Neutralizing / COVID-19 Vaccines / SARS-CoV-2 / COVID-19 / Antibodies, Viral Topics: Vaccines / Variants Limits: Female / Humans / Male Language: English Journal: Eur J Immunol Year: 2022 Document Type: Article Affiliation country: Eji.202149645