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Comparison of the medical burden of COVID-19 with seasonal influenza and measles outbreaks.
Nesselroth, Dafna; Yakub Hana, Hussam; Gleyzer, Alexandra; Simoes, Eric A F; Abu Atta, Mahdi; Ben Yehuda, Yoram; Bibi, Haim; Somekh, Ido; Somekh, Eli.
  • Nesselroth D; Department of Pediatrics, Mayanei Hayeshuah Medical Center, Bnei Brak, Israel.
  • Yakub Hana H; Affiliated with Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
  • Gleyzer A; Department of Pediatrics, Mayanei Hayeshuah Medical Center, Bnei Brak, Israel.
  • Simoes EAF; Affiliated with Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
  • Abu Atta M; Department of Pediatrics, Mayanei Hayeshuah Medical Center, Bnei Brak, Israel.
  • Ben Yehuda Y; Affiliated with Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
  • Bibi H; University of Colorado School of Medicine, Aurora, Colorado, USA.
  • Somekh I; Department of Pediatrics, Mayanei Hayeshuah Medical Center, Bnei Brak, Israel.
  • Somekh E; Affiliated with Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Acta Paediatr ; 111(3): 595-601, 2022 03.
Article in English | MEDLINE | ID: covidwho-1555863
ABSTRACT

AIM:

To examine and compare the medical burden of measles, influenza and COVID-19 outbreaks in the city of Bnei Brak, Israel.

METHODS:

The study was conducted during 2018-2021. The numbers of hospitalisations for these infections and their complications were recorded. Hospitalisation rates were determined by using the number of children residing in Bnei Brak and hospitalised with these infections during the study period as the numerators. The denominators were the estimated paediatric cases of measles, influenza and COVID-19 in Bnei Brak and were calculated under both pragmatic and conservative assumptions.

RESULTS:

A total of 247, 65 and 32 children were hospitalised with influenza, COVID-19 and measles respectively. Complication rates were higher following measles than after influenza and SARS-CoV-2 infections. Hospitalisation rates were 10% for measles, 0.6%-1.2% for influenza and 0.15% - 0.25% for COVID-19 infections. Relative risks (RR) with 95% confidence intervals (CI) for hospitalisation following measles compared with COVID-19 ranged from 42 (26.3-67.3) to 70.1 (43.8-112.1), while the relative risks for influenza hospitalisation ranged from 2.5 (1.83-3.41) to 8.2 (6.0-11.2), compared with COVID-19 infection.

CONCLUSION:

Hospitalisation rates and direct medical burdens of measles and influenza were significantly higher than those of COVID-19 infection in children.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Influenza, Human / COVID-19 / Measles Type of study: Observational study / Prognostic study Limits: Child / Humans Language: English Journal: Acta Paediatr Year: 2022 Document Type: Article Affiliation country: Apa.16210

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Influenza, Human / COVID-19 / Measles Type of study: Observational study / Prognostic study Limits: Child / Humans Language: English Journal: Acta Paediatr Year: 2022 Document Type: Article Affiliation country: Apa.16210