Synthetic biology enables field-deployable biosensors for water contaminants
TrAC Trends in Analytical Chemistry
; : 116507, 2021.
Article
in English
| ScienceDirect | ID: covidwho-1559776
ABSTRACT
Wastewater surveillance is a powerful tool to understand community profiling in terms of health monitoring. Tracking biomarkers such as inorganic and organic pollutants, drugs, and pathogens in wastewater gives a general idea about the lifestyle and health status of a population as well as pollutant exposure caused by various toxic chemicals. Notably, tracing pathogenic clues could help predict and prevent disease outbreaks such as the ongoing COVID-19 pandemic in communities. To this end, developing portable biosensing platforms will facilitate the on-site monitoring of water contamination without requiring complex equipment. New technological developments in synthetic biology have advanced both synthetic gene circuit-based biosensors and new in vitro detection strategies coupled with easy-to-interpret visualization methods. Here, we summarize the latest advances in synthetic biology tools and discuss how they enable the development of rapid, low-cost, ease-to-use and field-deployable biosensors for monitoring a variety of water contaminants and health-related biomarkers in the environment.
Full text:
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Collection:
Databases of international organizations
Database:
ScienceDirect
Language:
English
Journal:
TrAC Trends in Analytical Chemistry
Year:
2021
Document Type:
Article
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