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Reduced BNT162b2 Messenger RNA Vaccine Response in Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)-Naive Nursing Home Residents.
Canaday, David H; Carias, Lenore; Oyebanji, Oladayo A; Keresztesy, Debbie; Wilk, Dennis; Payne, Michael; Aung, Htin; St Denis, Kerri; Lam, Evan C; Rowley, Christopher F; Berry, Sarah D; Cameron, Cheryl M; Cameron, Mark J; Wilson, Brigid; Balazs, Alejandro B; Gravenstein, Stefan; King, Christopher L.
  • Canaday DH; Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.
  • Carias L; Geriatric Research, Education and Clinical Center, Cleveland Veterans Affairs Medical Center, Cleveland, Ohio, USA.
  • Oyebanji OA; Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.
  • Keresztesy D; Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.
  • Wilk D; Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.
  • Payne M; Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.
  • Aung H; Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.
  • St Denis K; Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.
  • Lam EC; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts, USA.
  • Rowley CF; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts, USA.
  • Berry SD; Division of Infectious Diseases, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.
  • Cameron CM; Marcus Institute for Aging Research, Hebrew SeniorLife, Boston, Massachusetts, USA.
  • Cameron MJ; Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.
  • Wilson B; Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.
  • Balazs AB; Geriatric Research, Education and Clinical Center, Cleveland Veterans Affairs Medical Center, Cleveland, Ohio, USA.
  • Gravenstein S; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts, USA.
  • King CL; Division of Geriatrics and Palliative Medicine, Alpert Medical School of Brown University, Providence, Rhode Island, USA.
Clin Infect Dis ; 73(11): 2112-2115, 2021 12 06.
Article in English | MEDLINE | ID: covidwho-1562012
ABSTRACT
After BNT162b2 messenger RNA vaccination, antibody levels to spike, receptor-binding domain, and virus neutralization were examined in 149 nursing home residents and 110 healthcare worker controls. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-naive nursing home residents' median post-second vaccine dose antibody neutralization titers are one-quarter that of SARS-CoV-2-naive healthcare workers.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: SARS-CoV-2 / COVID-19 Limits: Humans Language: English Journal: Clin Infect Dis Journal subject: Communicable Diseases Year: 2021 Document Type: Article Affiliation country: Cid

Full text: Available Collection: International databases Database: MEDLINE Main subject: SARS-CoV-2 / COVID-19 Limits: Humans Language: English Journal: Clin Infect Dis Journal subject: Communicable Diseases Year: 2021 Document Type: Article Affiliation country: Cid