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Unrepresentative big surveys significantly overestimated US vaccine uptake.
Bradley, Valerie C; Kuriwaki, Shiro; Isakov, Michael; Sejdinovic, Dino; Meng, Xiao-Li; Flaxman, Seth.
  • Bradley VC; Department of Statistics, University of Oxford, Oxford, UK.
  • Kuriwaki S; Department of Political Science, Stanford University, Stanford, CA, USA.
  • Isakov M; Harvard College, Harvard University, Cambridge, MA, USA.
  • Sejdinovic D; Department of Statistics, University of Oxford, Oxford, UK.
  • Meng XL; Department of Statistics, Harvard University, Cambridge, MA, USA.
  • Flaxman S; Department of Computer Science, University of Oxford, Oxford, UK. seth.flaxman@cs.ox.ac.uk.
Nature ; 600(7890): 695-700, 2021 12.
Article in English | MEDLINE | ID: covidwho-1562062
ABSTRACT
Surveys are a crucial tool for understanding public opinion and behaviour, and their accuracy depends on maintaining statistical representativeness of their target populations by minimizing biases from all sources. Increasing data size shrinks confidence intervals but magnifies the effect of survey bias an instance of the Big Data Paradox1. Here we demonstrate this paradox in estimates of first-dose COVID-19 vaccine uptake in US adults from 9 January to 19 May 2021 from two large surveys Delphi-Facebook2,3 (about 250,000 responses per week) and Census Household Pulse4 (about 75,000 every two weeks). In May 2021, Delphi-Facebook overestimated uptake by 17 percentage points (14-20 percentage points with 5% benchmark imprecision) and Census Household Pulse by 14 (11-17 percentage points with 5% benchmark imprecision), compared to a retroactively updated benchmark the Centers for Disease Control and Prevention published on 26 May 2021. Moreover, their large sample sizes led to miniscule margins of error on the incorrect estimates. By contrast, an Axios-Ipsos online panel5 with about 1,000 responses per week following survey research best practices6 provided reliable estimates and uncertainty quantification. We decompose observed error using a recent analytic framework1 to explain the inaccuracy in the three surveys. We then analyse the implications for vaccine hesitancy and willingness. We show how a survey of 250,000 respondents can produce an estimate of the population mean that is no more accurate than an estimate from a simple random sample of size 10. Our central message is that data quality matters more than data quantity, and that compensating the former with the latter is a mathematically provable losing proposition.
Subject(s)

Full text: Available Collection: International databases Database: MEDLINE Main subject: Vaccination / Health Care Surveys / COVID-19 Vaccines Type of study: Experimental Studies / Observational study / Prognostic study / Randomized controlled trials / Systematic review/Meta Analysis Topics: Vaccines Limits: Female / Humans / Male Country/Region as subject: North America Language: English Journal: Nature Year: 2021 Document Type: Article Affiliation country: S41586-021-04198-4

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Vaccination / Health Care Surveys / COVID-19 Vaccines Type of study: Experimental Studies / Observational study / Prognostic study / Randomized controlled trials / Systematic review/Meta Analysis Topics: Vaccines Limits: Female / Humans / Male Country/Region as subject: North America Language: English Journal: Nature Year: 2021 Document Type: Article Affiliation country: S41586-021-04198-4