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Risk Factors for In-hospital Mortality from Coronavirus Disease 2019 Infection Among Black Patients-An Urban Center Experience.
Bhargava, Ashish; Sharma, Mamta; Riederer, Kathleen; Fukushima, Elisa Akagi; Szpunar, Susanna M; Saravolatz, Louis.
  • Bhargava A; Department of Internal Medicine, Thomas Mackey Center for Infectious Diseases Research, Ascension St. John Hospital, Detroit, Michigan, USA.
  • Sharma M; Department of Internal Medicine, Thomas Mackey Center for Infectious Diseases Research, Ascension St. John Hospital, Detroit, Michigan, USA.
  • Riederer K; Department of Internal Medicine, Thomas Mackey Center for Infectious Diseases Research, Ascension St. John Hospital, Detroit, Michigan, USA.
  • Fukushima EA; Department of Internal Medicine, Thomas Mackey Center for Infectious Diseases Research, Ascension St. John Hospital, Detroit, Michigan, USA.
  • Szpunar SM; Department of Internal Medicine, Thomas Mackey Center for Infectious Diseases Research, Ascension St. John Hospital, Detroit, Michigan, USA.
  • Saravolatz L; Department of Internal Medicine, Thomas Mackey Center for Infectious Diseases Research, Ascension St. John Hospital, Detroit, Michigan, USA.
Clin Infect Dis ; 73(11): e4005-e4011, 2021 12 06.
Article in English | MEDLINE | ID: covidwho-1562130
Semantic information from SemMedBD (by NLM)
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Subject
risk factors
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Patients
2. COVID-19 PROCESS_OF inpatient
Subject
COVID-19
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inpatient
3. Virus CAUSES COVID-19
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Virus
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CAUSES
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COVID-19
4. Liver LOCATION_OF Severe disorder
Subject
Liver
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LOCATION_OF
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Severe disorder
5. Dementia PROCESS_OF Patients
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6. ABLEPHARON-MACROSTOMIA SYNDROME PROCESS_OF Patients
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ABLEPHARON-MACROSTOMIA SYNDROME
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7. Abnormal mental state COEXISTS_WITH Respiratory Distress Syndrom
Subject
Abnormal mental state
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COEXISTS_WITH
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Respiratory Distress Syndrom
8. Abnormal mental state COEXISTS_WITH Shock
Subject
Abnormal mental state
Predicate
COEXISTS_WITH
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Shock
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Patients
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Liver
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Severe disorder
13. Dementia PROCESS_OF Patients
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Dementia
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Patients
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Subject
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Patients
15. Abnormal mental state COEXISTS_WITH Respiratory Distress Syndrome, Adult
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16. Abnormal mental state COEXISTS_WITH Shock
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ABSTRACT

BACKGROUND:

Racial disparities are central in the national conversation about coronavirus disease 2019 (COVID-19) , with Black/African Americans being disproportionately affected. We assessed risk factors for death from COVID-19 among Black inpatients at an urban hospital in Detroit, Michigan.

METHODS:

This was a retrospective, single-center cohort study. We reviewed the electronic medical records of patients positive for severe acute respiratory syndrome coronavirus 2 (the COVID-19 virus) on qualitative polymerase chain reaction assay who were admitted between 8 March 2020 and 6 May 2020. The primary outcome was in-hospital mortality.

RESULTS:

The case fatality rate was 29.1% (122/419). The mean duration of symptoms prior to hospitalization was 5.3 (3.9) days. The incidence of altered mental status on presentation was higher among patients who died than those who survived, 43% vs 20.0%, respectively (P < .0001). From multivariable analysis, the odds of death increased with age (≥60 years), admission from a nursing facility, Charlson score, altered mental status, higher C-reactive protein on admission, need for mechanical ventilation, presence of shock, and acute respiratory distress syndrome.

CONCLUSIONS:

These demographic, clinical, and laboratory factors may help healthcare providers identify Black patients at highest risk for severe COVID-19-associated outcomes. Early and aggressive interventions among this at-risk population may help mitigate adverse outcomes.
Subject(s)
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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Type of study: Etiology study / Incidence study / Observational study / Prognostic study / Qualitative research / Risk factors Limits: Humans / Middle aged Language: English Journal: Clin Infect Dis Journal subject: Communicable Diseases Year: 2021 Document Type: Article Affiliation country: Cid

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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Type of study: Etiology study / Incidence study / Observational study / Prognostic study / Qualitative research / Risk factors Limits: Humans / Middle aged Language: English Journal: Clin Infect Dis Journal subject: Communicable Diseases Year: 2021 Document Type: Article Affiliation country: Cid