Pre-existing humoral immunity to human common cold coronaviruses negatively impacts the protective SARS-CoV-2 antibody response
Cell host & microbe
; 2021.
Article
in English
| EuropePMC | ID: covidwho-1564429
ABSTRACT
A major unresolved question is whether prior immunity to endemic, human common cold coronaviruses (hCCCoV) impacts susceptibility to SARS-CoV-2 infection. Lin et al. analyze hCCCoV antibodies in the same individuals before and after SARS-CoV-2 infection, finding pre-existing betacoronavirus antibodies may hinder SARS-CoV-2 effective immunity following infection.
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Collection:
Databases of international organizations
Database:
EuropePMC
Type of study:
Experimental Studies
Language:
English
Journal:
Cell host & microbe
Year:
2021
Document Type:
Article
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