Sub-acute hypersensitive reaction to botulinum toxin type A following Covid-19 vaccination: Case report and literature review.
Medicine (Baltimore)
; 100(49): e27787, 2021 Dec 10.
Article
in English
| MEDLINE | ID: covidwho-1566096
ABSTRACT
RATIONALE Botulinum toxin type A (BTA) is one of the most widely used injectable agents in cosmetic surgery. Corona virus disease 2019 (Covid-19) infection and vaccination, which can induce specific and nonspecific activation of the immune system, has been reported to induce delayed inflammatory reactions to previously injected hyaluronic acid fillers. However, there are no reports about the interaction between BTA and Covid-19. We aimed to report 2 sub-acute cases of allergic reactions to BTA in facial cosmesis following the Covid-19 vaccination. PATIENT CONCERN A 35-year-old and a 34-year-old female who has several previous BTA injections without any adverse effects experienced facial swelling, flu-like symptoms after BTA treatment following the Covid-19 vaccination. DIAGNOSE According to the typical clinical manifestation, a hypersensitive reaction to BTA was considered. INTERVENTION Corticosteroids and antihistamine were administered empirically. OUTCOMES:
The flu-like symptoms recovered over the next day, but the facial swelling gradually faded within 1 to 2 weeks. LESSONS A literature review was also conducted to summarize the hypersensitive actions to cosmesis related to Covid-19. We recommend BTA injection be administered at least 2 to 3âmonths after Covid-19 vaccination.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Botulinum Toxins, Type A
/
COVID-19 Vaccines
/
COVID-19
/
Hypersensitivity
Type of study:
Case report
/
Observational study
/
Prognostic study
/
Reviews
Topics:
Vaccines
Limits:
Adult
/
Female
/
Humans
Language:
English
Journal:
Medicine (Baltimore)
Year:
2021
Document Type:
Article
Affiliation country:
MD.0000000000027787
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