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Multisystem inflammatory syndrome in children associated with SARS-CoV-2: extracardiac radiological findings.
Ucan, Berna; Kaynak Sahap, Seda; Cinar, Hasibe Gokce; Tasci Yildiz, Yasemin; Uner, Cigdem; Polat, Meltem; Derinkuyu, Betul Emine.
  • Ucan B; Department of Pediatric Radiology, Dr. Sami Ulus Gynecology, Obstetricsand Child Health and Diseases Training and Research Hospital, Ankara, Turkey.
  • Kaynak Sahap S; Department of Pediatric Radiology, Dr. Sami Ulus Gynecology, Obstetricsand Child Health and Diseases Training and Research Hospital, Ankara, Turkey.
  • Cinar HG; Department of Pediatric Radiology, Dr. Sami Ulus Gynecology, Obstetricsand Child Health and Diseases Training and Research Hospital, Ankara, Turkey.
  • Tasci Yildiz Y; Department of Pediatric Radiology, Dr. Sami Ulus Gynecology, Obstetricsand Child Health and Diseases Training and Research Hospital, Ankara, Turkey.
  • Uner C; Department of Pediatric Radiology, Dr. Sami Ulus Gynecology, Obstetricsand Child Health and Diseases Training and Research Hospital, Ankara, Turkey.
  • Polat M; Department of Pediatric Infectious Disease, Dr. Sami Ulus Gynecology, Obstetrics and Child Health and Diseases Training and Research Hospital, Ankara, Turkey.
  • Derinkuyu BE; Department of Pediatric Radiology, Dr. Sami Ulus Gynecology, Obstetricsand Child Health and Diseases Training and Research Hospital, Ankara, Turkey.
Br J Radiol ; 95(1129): 20210570, 2022 Jan 01.
Article in English | MEDLINE | ID: covidwho-1566544
ABSTRACT

OBJECTIVE:

Multisystem inflammatory syndrome in children (MIS-C) is seen as a serious delayed complication of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The aim of this study was to describe the most common imaging features of MIS-C associated with SARS-CoV-2.

METHODS:

A retrospective review was made of the medical records and radiological imaging studies of 47 children (26 male, 21 female) in the age range of 25 months-15 years who were diagnosed with MIS-C between August 2020 and March 2021. Chest radiographs were available for all 47 patients, thorax ultrasound for 6, chest CT for 4, abdominal ultrasound for 42, abdomen CT for 9, neck ultrasound for 4, neck CT for 2, brain CT for 1, and brain MRI for 3.

RESULTS:

The most common finding on chest radiographs was perihilar-peribronchial thickening (46%). The most common findings on abdominal ultrasonography were mesenteric inflammation (42%), and hepatosplenomegaly (38%, 28%). Lymphadenopathy was determined in four patients who underwent neck ultrasound, one of whom had deep neck infection on CT. One patient had restricted diffusion and T2 hyperintensity involving the corpus callosum splenium on brain MRI, and one patient had epididymitis related with MIS-C.

CONCLUSION:

Pulmonary manifestations are uncommon in MIS-C. In the abdominal imaging, mesenteric inflammation, hepatosplenomegaly, periportal edema, ascites and bowel wall thickening are the most common findings. ADVANCES IN KNOWLEDGE The imaging findings of MIS-C are non-specific and can mimic many other pathologies. Radiologists should be aware that these findings may indicate the correct diagnosis of MIS-C.
Subject(s)

Full text: Available Collection: International databases Database: MEDLINE Main subject: Systemic Inflammatory Response Syndrome / COVID-19 Type of study: Observational study Topics: Long Covid Limits: Adolescent / Child / Child, preschool / Female / Humans / Male Language: English Journal: Br J Radiol Year: 2022 Document Type: Article Affiliation country: Bjr.20210570

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Systemic Inflammatory Response Syndrome / COVID-19 Type of study: Observational study Topics: Long Covid Limits: Adolescent / Child / Child, preschool / Female / Humans / Male Language: English Journal: Br J Radiol Year: 2022 Document Type: Article Affiliation country: Bjr.20210570