Imperative role of electron microscopy in toxicity assessment: A review.
Microsc Res Tech
; 85(5): 1976-1989, 2022 May.
Article
in English
| MEDLINE | ID: covidwho-1568138
ABSTRACT
Electron microscope (EM) was developed in 1931 and since then microscopical examination of both the biological and non-biological samples has been revolutionized. Modifications in electron microscopy techniques, such as scanning EM and transmission EM, have widened their applicability in the various sectors such as understanding of drug toxicity, development of mechanism, criminal site investigation, and characterization of the nano-molecule. The present review summarizes its role in important aspects such as toxicity assessment and disease diagnosis in special reference to SARS-COV2. In the biological system, EM studies have elucidated the impact of toxicants at the ultra-structural level in various tissue in conformity to physiological alterations. Thus, EM can be concluded as an important tool in toxicity assessment and disease prognosis.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
RNA, Viral
/
COVID-19
Type of study:
Prognostic study
Limits:
Humans
Language:
English
Journal:
Microsc Res Tech
Journal subject:
Diagnostic Imaging
Year:
2022
Document Type:
Article
Affiliation country:
Jemt.24029
Similar
MEDLINE
...
LILACS
LIS