Your browser doesn't support javascript.
Secondary bloodstream infection in critically ill patients with COVID-19.
Zhang, Junli; Lan, Peng; Yi, Jun; Yang, Changming; Gong, Xiaoyan; Ge, Huiqing; Xu, Xiaoling; Liu, Limin; Zhou, Jiancang; Lv, Fangfang.
  • Zhang J; Department of Infectious Diseases, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China.
  • Lan P; Department of Critical Care Medicine, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China.
  • Yi J; Department of Thoracic Surgery, Jingmen First People's Hospital, Hubei Province, China.
  • Yang C; Department of Anesthesiology, Jingmen First People's Hospital, Hubei Province, China.
  • Gong X; Department of Critical Care Medicine, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China.
  • Ge H; Department of Respiratory Therapy, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China.
  • Xu X; Department of Respiratory and Critical Care Medicine, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China.
  • Liu L; Dean's Office, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China.
  • Zhou J; Department of Critical Care Medicine, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China.
  • Lv F; Department of Infectious Diseases, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China.
J Int Med Res ; 49(12): 3000605211062783, 2021 Dec.
Article in English | MEDLINE | ID: covidwho-1571589
ABSTRACT

OBJECTIVE:

Secondary infection, especially bloodstream infection, is an important cause of death in critically ill patients with COVID-19. We aimed to describe secondary bloodstream infection (SBI) in critically ill adults with COVID-19 in the intensive care unit (ICU) and to explore risk factors related to SBI.

METHODS:

We reviewed all SBI cases among critically ill patients with COVID-19 from 12 February 2020 to 24 March 2020 in the COVID-19 ICU of Jingmen First People's Hospital. We compared risk factors associated with bloodstream infection in this study. All SBIs were confirmed by blood culture.

RESULTS:

We identified five cases of SBI among the 32 patients three with Enterococcus faecium, one mixed septicemia (E. faecium and Candida albicans), and one C. parapsilosis. There were no significant differences between the SBI group and non-SBI group. Significant risk factors for SBI were extracorporeal membrane oxygenation, central venous catheter, indwelling urethral catheter, and nasogastric tube.

CONCLUSIONS:

Our findings confirmed that the incidence of secondary infection, particularly SBI, and mortality are high among critically ill patients with COVID-19. We showed that long-term hospitalization and invasive procedures such as tracheotomy, central venous catheter, indwelling urethral catheter, and nasogastric tube are risk factors for SBI and other complications.
Subject(s)
Keywords

Full text: Available Collection: International databases Database: MEDLINE Main subject: Sepsis / Coinfection / COVID-19 Type of study: Prognostic study / Risk factors Limits: Adult / Humans Language: English Journal: J Int Med Res Year: 2021 Document Type: Article Affiliation country: 03000605211062783

Full text: Available Collection: International databases Database: MEDLINE Main subject: Sepsis / Coinfection / COVID-19 Type of study: Prognostic study / Risk factors Limits: Adult / Humans Language: English Journal: J Int Med Res Year: 2021 Document Type: Article Affiliation country: 03000605211062783