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A case report of ChAdOx1 nCoV-19 vaccine-associated encephalitis.
Takata, Junko; Durkin, Simon M; Wong, Solomon; Zandi, Michael S; Swanton, Josephine K; Corrah, Tumena W.
  • Takata J; Department of Infectious Diseases and Tropical Medicine, Northwick Park Hospital, London North West University Healthcare NHS Trust, Watford Road, Harrow, HA1 3UJ, UK.
  • Durkin SM; Department of Infectious Diseases and Tropical Medicine, Northwick Park Hospital, London North West University Healthcare NHS Trust, Watford Road, Harrow, HA1 3UJ, UK. simon.durkin@nhs.net.
  • Wong S; Harrow Crisis Team, Central and North West London NHS Foundation Trust, Northwick Park Hospital, Harrow, London, HA1 3UJ, UK.
  • Zandi MS; National Hospital for Neurology and Neurosurgery, University College London Hospitals NHS Foundation Trust, Queen Square, London, WC1N 3BG, UK.
  • Swanton JK; National Hospital for Neurology and Neurosurgery, University College London Hospitals NHS Foundation Trust, Queen Square, London, WC1N 3BG, UK.
  • Corrah TW; Department of Neurology, Northwick Park Hospital, London North West University Healthcare NHS Trust, Watford Road, Harrow, HA1 3UJ, UK.
BMC Neurol ; 21(1): 485, 2021 Dec 13.
Article in English | MEDLINE | ID: covidwho-1571746
ABSTRACT

BACKGROUND:

Vaccination against COVID-19 continues apace, but side-effects, both common and severe, continue to be reported. We report here the first published case of COVID-19 vaccine-related encephalitis. CASE PRESENTATION A young woman presented with acute neuropsychiatric symptoms following recent ChAdOx1 nCoV-19 vaccination. Extensive investigation did not identify alternative causes.

CONCLUSIONS:

This difficult case is here described, including presentation, investigation, and management. Further study on neuropsychiatric side-effects of COVID-19 vaccination, including investigation as to whether there may be a causal link, is required.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Encephalitis / COVID-19 Type of study: Case report Topics: Vaccines Limits: Female / Humans Language: English Journal: BMC Neurol Journal subject: Neurology Year: 2021 Document Type: Article Affiliation country: S12883-021-02517-w

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Encephalitis / COVID-19 Type of study: Case report Topics: Vaccines Limits: Female / Humans Language: English Journal: BMC Neurol Journal subject: Neurology Year: 2021 Document Type: Article Affiliation country: S12883-021-02517-w