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Cranial Nerve Involvement and Dysautonomia in Post-COVID-19 Guillain-Barré Syndrome.
Kakumoto, Toshiyuki; Kobayashi, Satoshi; Yuuki, Hayato; Kainaga, Mitsuhiro; Shirota, Yuichiro; Hamada, Masashi; Hashimoto Maeda, Meiko; Kubota, Akatsuki; Kawai, Mizuho; Saito, Masaaki; Ishiura, Hiroyuki; Toda, Tatsushi.
  • Kakumoto T; Department of Neurology, Graduate School of Medicine, The University of Tokyo, Japan.
  • Kobayashi S; Department of Neurology, Graduate School of Medicine, The University of Tokyo, Japan.
  • Yuuki H; Department of Neurology, Graduate School of Medicine, The University of Tokyo, Japan.
  • Kainaga M; Department of Neurology, Graduate School of Medicine, The University of Tokyo, Japan.
  • Shirota Y; Department of Neurology, Graduate School of Medicine, The University of Tokyo, Japan.
  • Hamada M; Department of Clinical Laboratory, The University of Tokyo Hospital, Japan.
  • Hashimoto Maeda M; Department of Neurology, Graduate School of Medicine, The University of Tokyo, Japan.
  • Kubota A; Department of Neurology, Graduate School of Medicine, The University of Tokyo, Japan.
  • Kawai M; Department of Neurology, Graduate School of Medicine, The University of Tokyo, Japan.
  • Saito M; Department of Neurology, Tokyo Kyosai Hospital, Japan.
  • Ishiura H; Department of Neurology, Tokyo Kyosai Hospital, Japan.
  • Toda T; Department of Neurology, Graduate School of Medicine, The University of Tokyo, Japan.
Intern Med ; 60(21): 3477-3480, 2021 Nov 01.
Article in English | MEDLINE | ID: covidwho-1572221
ABSTRACT
The clinical characteristics of Guillain-Barré syndrome (GBS) after coronavirus disease 2019 (COVID-19) remain unclear due to the small number of cases. We herein report a case of a Japanese patient with post-COVID-19 GBS who presented with facial and limb muscle weakness, sensory deficits, and autonomic dysfunction. Nerve conduction studies revealed demyelination. Head magnetic resonance imaging showed contrast enhancement in the bilateral facial nerves. Systemic management, including intubation, intravenous immunoglobulin therapy, and rehabilitation, improved the patient's condition. This was the first Japanese case of acute inflammatory demyelinating polyneuropathy after COVID-19 and was characterized by autonomic dysfunction and facial nerve enhancement.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Guillain-Barre Syndrome / Primary Dysautonomias / COVID-19 Type of study: Case report / Diagnostic study / Prognostic study Topics: Long Covid Limits: Humans Language: English Journal: Intern Med Journal subject: Internal Medicine Year: 2021 Document Type: Article Affiliation country: Internalmedicine.7355-21

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Guillain-Barre Syndrome / Primary Dysautonomias / COVID-19 Type of study: Case report / Diagnostic study / Prognostic study Topics: Long Covid Limits: Humans Language: English Journal: Intern Med Journal subject: Internal Medicine Year: 2021 Document Type: Article Affiliation country: Internalmedicine.7355-21