Your browser doesn't support javascript.
Factors Associated with ICU Admission in Patients with COVID-19: The GOL2DS Score.
Candelli, Marcello; Pignataro, Giulia; Ferrigno, Miriana; Cicchinelli, Sara; Torelli, Enrico; Gullì, Antonio; Sacco Fernandez, Marta; Piccioni, Andrea; Ojetti, Veronica; Covino, Marcello; Gasbarrini, Antonio; Antonelli, Massimo; Franceschi, Francesco.
  • Candelli M; Emergency Medicine Department-Fondazione, Universitaria Policlinico Agostino Gemelli-IRCCS-Catholic, University of Sacred Heart of Rome, 100168 Rome, Italy.
  • Pignataro G; Emergency Medicine Department-Fondazione, Universitaria Policlinico Agostino Gemelli-IRCCS-Catholic, University of Sacred Heart of Rome, 100168 Rome, Italy.
  • Ferrigno M; Emergency Medicine Department-Fondazione, Universitaria Policlinico Agostino Gemelli-IRCCS-Catholic, University of Sacred Heart of Rome, 100168 Rome, Italy.
  • Cicchinelli S; Emergency Medicine Department-Fondazione, Universitaria Policlinico Agostino Gemelli-IRCCS-Catholic, University of Sacred Heart of Rome, 100168 Rome, Italy.
  • Torelli E; Emergency Medicine Department-Fondazione, Universitaria Policlinico Agostino Gemelli-IRCCS-Catholic, University of Sacred Heart of Rome, 100168 Rome, Italy.
  • Gullì A; Emergency, Anesthesiological and Reanimation Sciences-Fondazione, Universitaria Policlinico Agostino Gemelli-IRCCS-Catholic, Faculty of Medicine, University of Sacred Heart of Rome, 100168 Rome, Italy.
  • Sacco Fernandez M; Emergency Medicine Department-Fondazione, Universitaria Policlinico Agostino Gemelli-IRCCS-Catholic, University of Sacred Heart of Rome, 100168 Rome, Italy.
  • Piccioni A; Emergency Medicine Department-Fondazione, Universitaria Policlinico Agostino Gemelli-IRCCS-Catholic, University of Sacred Heart of Rome, 100168 Rome, Italy.
  • Ojetti V; Emergency Medicine Department-Fondazione, Universitaria Policlinico Agostino Gemelli-IRCCS-Catholic, University of Sacred Heart of Rome, 100168 Rome, Italy.
  • Covino M; Emergency Medicine Department-Fondazione, Universitaria Policlinico Agostino Gemelli-IRCCS-Catholic, University of Sacred Heart of Rome, 100168 Rome, Italy.
  • Gasbarrini A; Department of Medical and Surgical Sciences-Fondazione, Universitaria Policlinico Agostino Gemelli-IRCCS-Catholic, University of Sacred Heart of Rome, 100168 Rome, Italy.
  • Antonelli M; Emergency, Anesthesiological and Reanimation Sciences-Fondazione, Universitaria Policlinico Agostino Gemelli-IRCCS-Catholic, Faculty of Medicine, University of Sacred Heart of Rome, 100168 Rome, Italy.
  • Franceschi F; Emergency Medicine Department-Fondazione, Universitaria Policlinico Agostino Gemelli-IRCCS-Catholic, University of Sacred Heart of Rome, 100168 Rome, Italy.
Medicina (Kaunas) ; 57(12)2021 Dec 12.
Article in English | MEDLINE | ID: covidwho-1572559
ABSTRACT
Background and

Objectives:

The COVID-19 pandemic has been shaking lives around the world for nearly two years. The discovery of highly effective vaccines has not been able to stop the transmission of the virus. SARS-CoV-2 shows completely different clinical manifestations. A large percentage (about 40%) of admitted patients require treatment in an intensive care unit (ICU). This study investigates the factors associated with admission of COVID-19 patients to the ICU and whether it is possible to obtain a score that can help the emergency physician to select the hospital ward. Materials and

Methods:

We retrospectively recorded 313 consecutive patients who were presented to the emergency department (ED) of our hospital and had a diagnosis of COVID-19 confirmed by polymerase chain reaction (PCR) on an oropharyngeal swab. We used multiple logistic regression to evaluate demographic, clinical, and laboratory data statistically associated with ICU admission. These variables were used to create a prognostic score for ICU admission. Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and receiver-operating characteristic curve (ROC) of the score for predicting ICU admission during hospitalization were calculated.

Results:

Of the variables evaluated, only blood type A (p = 0.003), PaO2/FiO2 (p = 0.002), LDH (p = 0.004), lactate (p = 0.03), dyspnea (p = 0.03) and SpO2 (p = 0.0228) were significantly associated with ICU admission after adjusting for sex, age and comorbidity using multiple logistic regression analysis. We used these variables to create a prognostic score called GOL2DS (group A, PaO2/FiO2, LDH, lactate and dyspnea, and SpO2), which had high accuracy in predicting ICU admission (AUROC 0.830 [95% CI, 0.791-0.892).

Conclusions:

In our single-center experience, the GOL2DS score could be useful in identifying patients at high risk for ICU admission.
Subject(s)
Keywords

Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Type of study: Diagnostic study / Experimental Studies / Observational study / Prognostic study Topics: Vaccines Limits: Humans Language: English Journal subject: Medicine Year: 2021 Document Type: Article Affiliation country: Medicina57121356

Similar

MEDLINE

...
LILACS

LIS


Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Type of study: Diagnostic study / Experimental Studies / Observational study / Prognostic study Topics: Vaccines Limits: Humans Language: English Journal subject: Medicine Year: 2021 Document Type: Article Affiliation country: Medicina57121356