Your browser doesn't support javascript.
Decreased Fetal Movements: A Sign of Placental SARS-CoV-2 Infection with Perinatal Brain Injury.
Favre, Guillaume; Mazzetti, Sara; Gengler, Carole; Bertelli, Claire; Schneider, Juliane; Laubscher, Bernard; Capoccia, Romina; Pakniyat, Fatemeh; Ben Jazia, Inès; Eggel-Hort, Béatrice; de Leval, Laurence; Pomar, Léo; Greub, Gilbert; Baud, David; Giannoni, Eric.
  • Favre G; Materno-Fetal and Obstetrics Research Unit, Department Woman-Mother-Child, Lausanne University Hospital, University of Lausanne, 1011 Lausanne, Switzerland.
  • Mazzetti S; Clinic of Pediatrics, Department Mother-Woman-Child, Lausanne University Hospital, University of Lausanne, 1011 Lausanne, Switzerland.
  • Gengler C; Department of Laboratory Medicine and Pathology, Institute of Pathology, Lausanne University Hospital, University of Lausanne, 1011 Lausanne, Switzerland.
  • Bertelli C; Institute of Microbiology, Lausanne University Hospital, University of Lausanne, 1011 Lausanne, Switzerland.
  • Schneider J; Clinic of Neonatology, Department Mother-Woman-Child, Lausanne University Hospital, University of Lausanne, 1011 Lausanne, Switzerland.
  • Laubscher B; Clinic of Pediatrics, Department Mother-Woman-Child, Lausanne University Hospital, University of Lausanne, 1011 Lausanne, Switzerland.
  • Capoccia R; Department of Pediatrics, Réseau Hospitalier Neuchâtelois, 2000 Neuchâtel, Switzerland.
  • Pakniyat F; Department of Obstetrics and Gynecology, Réseau Hospitalier Neuchâtelois, 2000 Neuchatel, Switzerland.
  • Ben Jazia I; Department of Obstetrics and Gynecology, Réseau Hospitalier Neuchâtelois, 2000 Neuchatel, Switzerland.
  • Eggel-Hort B; Department of Obstetrics and Gynecology, Réseau Hospitalier Neuchâtelois, 2000 Neuchatel, Switzerland.
  • de Leval L; Department of Obstetrics and Gynecology, Hôpital du Valais-Centre Hospitalier du Valais Romand-Site de Sion, 1951 Sion, Switzerland.
  • Pomar L; Department of Laboratory Medicine and Pathology, Institute of Pathology, Lausanne University Hospital, University of Lausanne, 1011 Lausanne, Switzerland.
  • Greub G; Materno-Fetal and Obstetrics Research Unit, Department Woman-Mother-Child, Lausanne University Hospital, University of Lausanne, 1011 Lausanne, Switzerland.
  • Baud D; Midwifery Department, School of Health Sciences (HESAV), University of Applied Sciences and Arts Western Switzerland, 1011 Lausanne, Switzerland.
  • Giannoni E; Institute of Microbiology, Lausanne University Hospital, University of Lausanne, 1011 Lausanne, Switzerland.
Viruses ; 13(12)2021 12 15.
Article in English | MEDLINE | ID: covidwho-1572671
ABSTRACT
Neonatal COVID-19 is rare and mainly results from postnatal transmission. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), however, can infect the placenta and compromise its function. We present two cases of decreased fetal movements and abnormal fetal heart rhythm 5 days after mild maternal COVID-19, requiring emergency caesarean section at 29 + 3 and 32 + 1 weeks of gestation, and leading to brain injury. Placental examination revealed extensive and multifocal chronic intervillositis, with intense cytoplasmic positivity for SARS-CoV-2 spike antibody and SARS-CoV-2 detection by RT-qPCR. Vertical transmission was confirmed in one case, and both neonates developed extensive cystic peri-ventricular leukomalacia.
Subject(s)
Keywords
Fulltext
Print
XML
PubMed Links
Search on Google

Full text: Available Collection: International databases Database: MEDLINE Main subject: Placenta / Pregnancy Complications, Infectious / Brain Injuries / COVID-19 Type of study: Case report Topics: Long Covid Limits: Adult / Female / Humans / Infant, Newborn / Pregnancy Language: English Year: 2021 Document Type: Article Affiliation country: V13122517

Similar

MEDLINE
LILACS
LIS
Fulltext
Print
XML
PubMed Links
Search on Google

Full text: Available Collection: International databases Database: MEDLINE Main subject: Placenta / Pregnancy Complications, Infectious / Brain Injuries / COVID-19 Type of study: Case report Topics: Long Covid Limits: Adult / Female / Humans / Infant, Newborn / Pregnancy Language: English Year: 2021 Document Type: Article Affiliation country: V13122517