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Characteristics and patterns of care of endometrial cancer before and during COVID-19 pandemic.
Bogani, Giorgio; Scambia, Giovanni; Cimmino, Chiara; Fanfani, Francesco; Costantini, Barbara; Loverro, Matteo; Ferrandina, Gabriella; Landoni, Fabio; Bazzurini, Luca; Grassi, Tommaso; Vitobello, Domenico; Siesto, Gabriele; Perrone, Anna Myriam; Zanagnolo, Vanna; De Iaco, Pierandrea; Multinu, Francesco; Ghezzi, Fabio; Casarin, Jvan; Berretta, Roberto; Capozzi, Vito A; Zupi, Errico; Centini, Gabriele; Pellegrino, Antonio; Corso, Silvia; Stevenazzi, Guido; Montoli, Serena; Boschi, Anna Chiara; Comerci, Giuseppe; Greco, Pantaleo; Martinello, Ruby; Sopracordevole, Francesco; Giorda, Giorgio; Simoncini, Tommaso; Caretto, Marta; Sartori, Enrico; Ferrari, Federico; Cianci, Antonio; Sarpietro, Giuseppe; Matarazzo, Maria Grazia; Zullo, Fulvio; Bifulco, Giuseppe; Morelli, Michele; Ferrero, Annamaria; Biglia, Nicoletta; Barra, Fabio; Ferrero, Simone; Leone Roberti Maggiore, Umberto; Cianci, Stefano; Chiantera, Vito; Ercoli, Alfredo.
  • Bogani G; Gynecologic Oncology Unit, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milan, Italy. giorgiobogani@yahoo.it.
  • Scambia G; Gynecologic Oncology Unit, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
  • Cimmino C; Department of Obstetrics and Gynaecology, University of Insubria, F. chia.cimmino@gmail.com Del Ponte Hospital, Varese, Italy. chia.cimmino@gmail.com.
  • Fanfani F; Gynecologic Oncology Unit, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
  • Costantini B; Gynecologic Oncology Unit, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
  • Loverro M; Gynecologic Oncology Unit, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
  • Ferrandina G; Gynecologic Oncology Unit, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
  • Landoni F; Department of Obstetrics and Gynaecology, San Gerardo Hospital, Monza, Italy.
  • Bazzurini L; Department of Obstetrics and Gynaecology, San Gerardo Hospital, Monza, Italy.
  • Grassi T; Department of Obstetrics and Gynaecology, San Gerardo Hospital, Monza, Italy.
  • Vitobello D; Unit of Gynecology, Humanitas Cancer Center, Humanitas Clinical and Research Center - IRCCS, Milan, Italy.
  • Siesto G; Unit of Gynecology, Humanitas Cancer Center, Humanitas Clinical and Research Center - IRCCS, Milan, Italy.
  • Perrone AM; Unit of Gynecology, AOU S. Orsola-Malpighi, Bologna, Italy.
  • Zanagnolo V; Department of Gynecologic Oncology, IEO, European Institute of Oncology IRCCS, Milan, Italy.
  • De Iaco P; Unit of Gynecology, AOU S. Orsola-Malpighi, Bologna, Italy.
  • Multinu F; Department of Gynecologic Oncology, IEO, European Institute of Oncology IRCCS, Milan, Italy.
  • Ghezzi F; Department of Obstetrics and Gynaecology, University of Insubria, F. Del Ponte Hospital, Varese, Italy.
  • Casarin J; Department of Obstetrics and Gynaecology, University of Insubria, F. Del Ponte Hospital, Varese, Italy.
  • Berretta R; Department of Obstetrics and Gynaecology, University of Parma, Parma, Italy.
  • Capozzi VA; Department of Obstetrics and Gynaecology, University of Parma, Parma, Italy.
  • Zupi E; Department of Obstetrics and Gynaecology, University of Siena, Siena, Italy.
  • Centini G; Department of Obstetrics and Gynaecology, University of Siena, Siena, Italy.
  • Pellegrino A; Department of Obstetrics and Gynaecology, ASST Lecco - Ospedale Alessandro Manzoni, Lecco, Italy.
  • Corso S; Department of Obstetrics and Gynaecology, ASST Lecco - Ospedale Alessandro Manzoni, Lecco, Italy.
  • Stevenazzi G; Department of Obstetrics and Gynaecology, ASST OVEST MI, Legnano (Milan) Hospital, Legnano, Italy.
  • Montoli S; Department of Obstetrics and Gynaecology, ASST OVEST MI, Legnano (Milan) Hospital, Legnano, Italy.
  • Boschi AC; Department of Obstetrics and Gynaecology, AUSL Romagna, Ospedale "Santa Maria delle Croci", Ravenna, Italy.
  • Comerci G; Department of Obstetrics and Gynaecology, AUSL Romagna, Ospedale "Santa Maria delle Croci", Ravenna, Italy.
  • Greco P; Clinica Ostetrica e Ginecologica - Dipartimento Scienze Mediche - Università di Ferrara, Ferarra, Italy.
  • Martinello R; Clinica Ostetrica e Ginecologica - Dipartimento Scienze Mediche - Università di Ferrara, Ferarra, Italy.
  • Sopracordevole F; Gynecological Oncology Unit, Centro di Riferimento Oncologico - National Cancer Institute, Aviano, Italy.
  • Giorda G; Gynecological Oncology Unit, Centro di Riferimento Oncologico - National Cancer Institute, Aviano, Italy.
  • Simoncini T; Division of Obstetrics and Gynecology, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
  • Caretto M; Division of Obstetrics and Gynecology, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
  • Sartori E; Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.
  • Ferrari F; Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.
  • Cianci A; Department of General Surgery and Medical Surgical Specialties, Gynecological Clinic, University of Catania, Catania, Italy.
  • Sarpietro G; Department of General Surgery and Medical Surgical Specialties, Gynecological Clinic, University of Catania, Catania, Italy.
  • Matarazzo MG; Department of General Surgery and Medical Surgical Specialties, Gynecological Clinic, University of Catania, Catania, Italy.
  • Zullo F; Department of Obstetrics and Gynaecology, Azienda Ospedaliera Universitaria - Federico II, Naples, Italy.
  • Bifulco G; Department of Obstetrics and Gynaecology, Azienda Ospedaliera Universitaria - Federico II, Naples, Italy.
  • Morelli M; Department of Obstetrics and Gynaecology, AO "S.S. Annunziata", Cosenza, Italy.
  • Ferrero A; Academic Department of Obstetrics and Gynecology, Mauriziano Hospital, Torino, Italy.
  • Biglia N; Academic Department of Obstetrics and Gynecology, Mauriziano Hospital, Torino, Italy.
  • Barra F; Academic Unit of Obstetrics and Gynecology, IRCCS Ospedale Policlinico San Martino, Genova, Italy.
  • Ferrero S; Academic Unit of Obstetrics and Gynecology, IRCCS Ospedale Policlinico San Martino, Genova, Italy.
  • Leone Roberti Maggiore U; Gynecologic Oncology Unit, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milan, Italy.
  • Cianci S; Unit of Gynecology and Obstetrics, Department of Human Pathology in Adulthood and Childhood "G. Barresi", University Hospital G. Martino, University of Messina, Messina, Italy.
  • Chiantera V; Department of Gynecologic Oncology, University of Palermo, Palermo, Italy.
  • Ercoli A; Unit of Gynecology and Obstetrics, Department of Human Pathology in Adulthood and Childhood "G. Barresi", University Hospital G. Martino, University of Messina, Messina, Italy.
J Gynecol Oncol ; 33(1): e10, 2022 01.
Article in English | MEDLINE | ID: covidwho-1573883
ABSTRACT

OBJECTIVE:

Coronavirus disease 2019 (COVID-19) outbreak has correlated with the disruption of screening activities and diagnostic assessments. Endometrial cancer (EC) is one of the most common gynecological malignancies and it is often detected at an early stage, because it frequently produces symptoms. Here, we aim to investigate the impact of COVID-19 outbreak on patterns of presentation and treatment of EC patients.

METHODS:

This is a retrospective study involving 54 centers in Italy. We evaluated patterns of presentation and treatment of EC patients before (period 1 March 1, 2019 to February 29, 2020) and during (period 2 April 1, 2020 to March 31, 2021) the COVID-19 outbreak.

RESULTS:

Medical records of 5,164 EC patients have been retrieved 2,718 and 2,446 women treated in period 1 and period 2, respectively. Surgery was the mainstay of treatment in both periods (p=0.356). Nodal assessment was omitted in 689 (27.3%) and 484 (21.2%) patients treated in period 1 and 2, respectively (p<0.001). While, the prevalence of patients undergoing sentinel node mapping (with or without backup lymphadenectomy) has increased during the COVID-19 pandemic (46.7% in period 1 vs. 52.8% in period 2; p<0.001). Overall, 1,280 (50.4%) and 1,021 (44.7%) patients had no adjuvant therapy in period 1 and 2, respectively (p<0.001). Adjuvant therapy use has increased during COVID-19 pandemic (p<0.001).

CONCLUSION:

Our data suggest that the COVID-19 pandemic had a significant impact on the characteristics and patterns of care of EC patients. These findings highlight the need to implement healthcare services during the pandemic.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Endometrial Neoplasms / COVID-19 Type of study: Observational study / Risk factors Limits: Female / Humans Language: English Journal: J Gynecol Oncol Year: 2022 Document Type: Article Affiliation country: Jgo.2022.33.e10

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Endometrial Neoplasms / COVID-19 Type of study: Observational study / Risk factors Limits: Female / Humans Language: English Journal: J Gynecol Oncol Year: 2022 Document Type: Article Affiliation country: Jgo.2022.33.e10