Analyzing correlation of clinical severity of COVID-19 with other biochemical parameters: a retrospective study from Pakistan
Tohoku Journal of Experimental Medicine
; 255(4):315-323, 2021.
Article
in English
| GIM | ID: covidwho-1756056
ABSTRACT
The third wave of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is causing damage all over the world, especially in Pakistan and India. Although vaccines are available and preventive measures are being taken, but SARS-CoV-2 is unstoppable. Currently, there are around 841,636 positive cases in Pakistan and 18,429 deaths, whereas, in India, both are high. From April 8th to 12th, 2021, nasopharyngeal swabs of 190 patients were submitted to PRL (PACP) lab for the SARS-CoV-2 testing, and blood samples were collected at the Mayo Hospital lab for ferritin, D-dimers, lactate dehydrogenase (LDH), and C-reactive protein (CRP) testing. This study observed that coronavirus disease 2019 (COVID-19) was more likely in individuals aged 51-60 than 61-70. In addition, our study found that COVID-19 patients exhibited a statistically significant increase in levels of ferritin, D-dimers, LDH, and CRP. In addition, this study revealed that SARS-CoV-2 relapsed. Furthermore, we concluded that these biochemical parameters are useful indicators for severity of COVID-19.
9001-60-9; 9007-41-4; 9007-73-2; lactate dehydrogenase; coronavirus disease 2019; viral diseases; clinical aspects; biochemistry; retrospective studies; death; mortality; C-reactive protein; ferritin; severe course; biological markers; human diseases; acute course; Severe acute respiratory syndrome coronavirus 2; man; Pakistan; Severe acute respiratory syndrome-related coronavirus; Betacoronavirus; Coronavirinae; Coronaviridae; Nidovirales; positive-sense ssRNA Viruses; ssRNA Viruses; RNA Viruses; viruses; Commonwealth of Nations; lower-middle income countries; medium Human Development Index countries; South Asia; Asia; Homo; Hominidae; primates; mammals; vertebrates; Chordata; animals; eukaryotes; SARS-CoV-2; viral infections; clinical picture; death rate; biomarkers
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Collection:
Databases of international organizations
Database:
GIM
Type of study:
Observational study
/
Prognostic study
Language:
English
Journal:
Tohoku Journal of Experimental Medicine
Year:
2021
Document Type:
Article
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