Epidemiology of Pemphigus.
JID Innov
; 1(1): 100004, 2021 Mar.
Article
in English
| MEDLINE | ID: covidwho-2298198
ABSTRACT
Pemphigus is an epidemiologically heterogeneous group of autoimmune bullous diseases comprising pemphigus vulgaris (PV), pemphigus foliaceus, paraneoplastic pemphigus, IgA pemphigus, and pemphigus herpetiformis. Recently, our knowledge about the frequency of pemphigus, which is highly variable between different populations, has considerably expanded, and the first non-HLA genes associated with PV have been identified. In addition, a variety of comorbidities, including other autoimmune diseases, hematological malignancies, and psoriasis, have been described in this variant. Here, initial data about the impact of COVID-19 on this fragile patient population are discussed and perspectives for future epidemiological studies are outlined.
ACE, angiotensin-converting enzyme; AIBD, autoimmune bullous disease; CAAR, chimeric autoantibody receptor; CI, confidence interval; DSG, desmoglein; EADV, European Academy of Dermatology and Venereology; EC, extracellular; EMA, European Medicines Agency; FS, fogo selvage; HR, hazard ratio; ICD, International Classification of Diseases; PF, pemphigus foliaceus; PNP, paraneoplastic pemphigus; PV, pemphigus vulgaris; SMR, standardized mortality ratio
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Type of study:
Observational study
Topics:
Variants
Language:
English
Journal:
JID Innov
Year:
2021
Document Type:
Article
Affiliation country:
J.xjidi.2021.100004
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