Corneal Graft Rejection After Inactivated SARS-CoV-2 Vaccine: Case Report.
Cornea
; 41(4): 502-504, 2022 Apr 01.
Article
in English
| MEDLINE | ID: covidwho-1575618
ABSTRACT
PURPOSE:
Our aim was to report the case of endothelial corneal allograft rejection after inactivated severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine with an atypical presentation.METHODS:
This was a case report.RESULTS:
A 63-year-old woman with previous penetrating keratoplasty and laser in situ keratomileusis presented with clinical signs of endothelial corneal graft rejection 24 hours after CoronaVac (SinoVac Biotech, Beijing/China) vaccine. Slitlamp examination showed corneal edema and interface fluid accumulation. It was partially resolved after treatment with topical corticosteroids and polydimethylsiloxane.CONCLUSIONS:
Corneal allograft rejection was already reported after another SARS-CoV-2 vaccine. This is the first report in the literature describing a possible association with inactivated SARS-CoV-2 vaccine and corneal allograft rejection, especially with laser in situ keratomileusis interface fluid accumulation presentation. Ophthalmologists should be aware of this potential complication.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Vaccines, Inactivated
/
Keratoplasty, Penetrating
/
COVID-19 Vaccines
/
SARS-CoV-2
/
COVID-19
/
Graft Rejection
Type of study:
Case report
/
Diagnostic study
/
Observational study
/
Prognostic study
Topics:
Vaccines
Limits:
Female
/
Humans
/
Middle aged
Language:
English
Journal:
Cornea
Year:
2022
Document Type:
Article
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