A scalable approach to topographically mediated antimicrobial surfaces based on diamond.
J Nanobiotechnology
; 19(1): 458, 2021 Dec 28.
Article
in English
| MEDLINE | ID: covidwho-1577211
ABSTRACT
Bio-inspired Topographically Mediated Surfaces (TMSs) based on high aspect ratio nanostructures have recently been attracting significant attention due to their pronounced antimicrobial properties by mechanically disrupting cellular processes. However, scalability of such surfaces is often greatly limited, as most of them rely on micro/nanoscale fabrication techniques. In this report, a cost-effective, scalable, and versatile approach of utilizing diamond nanotechnology for producing TMSs, and using them for limiting the spread of emerging infectious diseases, is introduced. Specifically, diamond-based nanostructured coatings are synthesized in a single-step fabrication process with a densely packed, needle- or spike-like morphology. The antimicrobial proprieties of the diamond nanospike surface are qualitatively and quantitatively analyzed and compared to other surfaces including copper, silicon, and even other diamond surfaces without the nanostructuring. This surface is found to have superior biocidal activity, which is confirmed via scanning electron microscopy images showing definite and widespread destruction of E. coli cells on the diamond nanospike surface. Consistent antimicrobial behavior is also observed on a sample prepared seven years prior to testing date.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Diamond
/
Coated Materials, Biocompatible
/
Nanostructures
/
Anti-Bacterial Agents
Type of study:
Qualitative research
Language:
English
Journal:
J Nanobiotechnology
Year:
2021
Document Type:
Article
Affiliation country:
S12951-021-01218-3
Similar
MEDLINE
...
LILACS
LIS