Pregnancy outcomes after maternal covid-19 vaccination during pregnancy: Preliminary data
Akusherstvo i Ginekologiya (Russian Federation)
; - (11):5-8, 2021.
Article
in English, Russian
| EMBASE | ID: covidwho-1579565
ABSTRACT
COVID-19 significantly raises risk during pregnancy. Currently, available evidence suggests that pregnant women are more susceptible to COVID-19 than the general population [1]. Pregnant women with COVID-19 are at increased risk of severe illness, death, and adverse pregnancy outcomes [2–4]. The most effective way to prevent the disease is vaccination. Current research evidence suggests that approved COVID-19 vaccines are safe, effective, and unlikely to pose any dangers to pregnant women or fetuses [5]. National and international associations issued guidelines supporting COVID-19 vaccination in pregnant and lactating women [6]. In the Russian Federation, vaccination of pregnant women with the Gam-COVID-Vac (Sputnik V) vaccine has been permitted since June 2021. Results of animal preclinical studies suggest no adverse impact of the Gam-COVID-Vac vaccine on the course of pregnancy and fetal, embryonic, and prenatal development of offspring [7]. Objective:
This study aimed to analyze pregnancy complications after maternal COVID-19 vaccination with domestic vaccines during pregnancy. Region, 75 from Trans-Baikal Krai, 76 from Yaroslavl Region, 89 from Yamalo-Nenets Autonomous Okrug, and 92 from Sevastopol. Most of the women were vaccinated with Gam-COVID-Vac (Sputnik V) vaccine (91.6%) and received two vaccine doses (57.9%). Most of the patients were vaccinated in the first trimester of pregnancy, including 683 (88.4%), 51 (6.6%), and 39 (5%) before 12 weeks, from 12 to 22 weeks, and after 22 weeks of pregnancy, respectively.
adult; animal, experiment; animal, model; complication; controlled, study; coronavirus, disease, 2019; drug, therapy; embryo; female; fetus; first, trimester, pregnancy; human; Nenets, Autonomous, Okrug; nonhuman; note; preclinical, study; pregnancy, complication; pregnancy, outcome; pregnant, woman; preliminary, data; prenatal, development; prevention; progeny; vaccination; sputnik, v, vaccine
Full text:
Available
Collection:
Databases of international organizations
Database:
EMBASE
Topics:
Vaccines
Language:
English
/
Russian
Journal:
Akusherstvo i Ginekologiya (Russian Federation)
Year:
2021
Document Type:
Article
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