Performance of six SARS-CoV-2 RNA detection systems in symptomatic and asymptomatic pediatric and maternal patients.
Future Virol
; 2021 Nov.
Article
in English
| MEDLINE | ID: covidwho-1581479
ABSTRACT
Aim:
This study evaluated the real-world performance of six test systems for detection of SARS-CoV-2 in 138 pediatric and 110 adult maternal patients. Materials &methods:
Nasopharyngeal swabs were tested directly using the Aptima™ SARS-CoV-2 (Aptima) and Simplexa™ COVID-19 Direct (Simplexa), and with Altona RealStar® RT-PCR and CDC RT-PCR with nucleic acid extracted on the Roche® MagNA Pure 96 (Altona-MP96) or bioMérieux EMAG® (Altona-EMAG). Results/Conclusion:
Overall percent-positive and percent-negative agreements among the six test systems were, respectively Aptima 94.8 and 100%; Altona-MP96 96.5 and 99.3%; CDC-MP96 100 and 99.3%; Altona-EMAG 86.1 and 100%; CDC-EMAG 98.2 and 100%; Simplexa 87 and 99.2%. The six test systems showed agreement ranging from 92.7 (κ = 0.85) to 98.8% (κ = 0.98).
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Type of study:
Experimental Studies
Language:
English
Year:
2021
Document Type:
Article
Affiliation country:
Fvl-2021-0311
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