Association of androgenetic alopecia and severity of coronavirus disease 2019.
J Cosmet Dermatol
; 21(3): 874-879, 2022 Mar.
Article
in English
| MEDLINE | ID: covidwho-1583491
ABSTRACT
OBJECTIVE:
To establish the association of androgenetic alopecia (AGA) and the severity of coronavirus disease 2019 (COVID-19).DESIGN:
Observational study.METHODOLOGY:
A total of 300 hospitalized patients of COVID-19 were included. Scoring of AGA was done, and severity of COVID-19 was measured as better and worse hospital outcomes. Correlation between severity of AGA and severity of COVID-19 was noted.RESULTS:
Out of 300 patients, 220 (73.33%) were male and 80 (26.67%) were female. In males, mild-to-moderate Hamilton-Norwood scale (HNS<3) and severe alopecia (HNS3-7) were noted among 43(20%) and 177(80.55%) patients, respectively. In females, 43(54%) had no AGA while 37(46%) had AGA. In 37 females with AGA, mild-to-moderate (Ludwig scale <2) and severe alopecia (Ludwig scale 2-3) were seen in 9(24.32%) and 28(75.68%) patients, respectively. We report a significant increase in frequency (95%) and severity of AGA and worse outcomes in males (p-value 0.000, chi-square 18.90) compared with females (46%) (p-value 0.273, chi-square 7.544), with notable adverse COVID-19 disease outcomes in the younger age group of men and also in few women of younger age group suffering from AGA without any comorbidities.CONCLUSION:
Our study shows a significant increase in frequency and severity of AGA and worse outcomes in men compared with women. There was a significant association between AGA severity and hospital disease outcome in men compared with women. Younger age group patients with severe AGA particularly men also faced adverse outcomes while having no known comorbidities, supporting the hypothesis that anti-androgen drugs might be valuable in patients of COVID-19.Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
COVID-19
Type of study:
Observational study
/
Prognostic study
Limits:
Female
/
Humans
/
Male
Language:
English
Journal:
J Cosmet Dermatol
Journal subject:
Dermatology
Year:
2022
Document Type:
Article
Affiliation country:
Jocd.14683
Similar
MEDLINE
...
LILACS
LIS