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Emergency air evacuation of patients with acute respiratory failure due to SARS-CoV-2 from Mayotte to Reunion Island.
Berguigua, Hamza; Iche, Ludovic; Roche, Philippe; Aubert, Cyril; Blondé, Renaud; Legrand, Antoine; Puech, Bérénice; Combe, Chloé; Vidal, Charles; Caron, Margot; Jaffar-Bandjee, Marie-Christine; Caralp, Christophe; Oulehri, Nora; Kerambrun, Hugo; Allyn, Jérôme; Boué, Yvonnick; Allou, Nicolas.
  • Berguigua H; Department of Emergency, Center Hospitalier Universitaire Felix Guyon, Saint Denis, France.
  • Iche L; Department of Emergency, Center Hospitalier de Mayotte, Mamoudzou, France.
  • Roche P; Department of Emergency, Center Hospitalier de Mayotte, Mamoudzou, France.
  • Aubert C; Department of Emergency, Center Hospitalier Universitaire Felix Guyon, Saint Denis, France.
  • Blondé R; Réanimation Polyvalente, Center Hospitalier de Mayotte, Mamoudzou, France.
  • Legrand A; Réanimation polyvalente, Center Hospitalier Universitaire Felix Guyon Allée des Topazes Saint Denis, France.
  • Puech B; Réanimation polyvalente, Center Hospitalier Universitaire Felix Guyon Allée des Topazes Saint Denis, France.
  • Combe C; Réanimation polyvalente, Center Hospitalier Universitaire Felix Guyon Allée des Topazes Saint Denis, France.
  • Vidal C; Réanimation polyvalente, Center Hospitalier Universitaire Felix Guyon Allée des Topazes Saint Denis, France.
  • Caron M; Réanimation polyvalente, Center Hospitalier Universitaire Felix Guyon Allée des Topazes Saint Denis, France.
  • Jaffar-Bandjee MC; Microbiologie, Centre Hospitalier Universitaire Felix Guyon Allée des Topazes Saint Denis, France.
  • Caralp C; Department of Emergency, Center Hospitalier de Mayotte, Mamoudzou, France.
  • Oulehri N; Department of Emergency, Center Hospitalier de Mayotte, Mamoudzou, France.
  • Kerambrun H; Réanimation Polyvalente, Center Hospitalier de Mayotte, Mamoudzou, France.
  • Allyn J; Réanimation polyvalente, Center Hospitalier Universitaire Felix Guyon Allée des Topazes Saint Denis, France.
  • Boué Y; Département d'Informatique Clinique, Centre Hospitalier Universitaire Felix Guyon Allée des Topazes, Saint Denis, France.
  • Allou N; Réanimation Polyvalente, Center Hospitalier de Mayotte, Mamoudzou, France.
Medicine (Baltimore) ; 100(48): e27881, 2021 Dec 03.
Article in English | MEDLINE | ID: covidwho-1583961
ABSTRACT
ABSTRACT In February 2021, an explosion of cases of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pneumonia overwhelmed the only hospital in Mayotte. To report a case series of patients with acute respiratory failure (ARF) due to SARS-CoV-2 who were evacuated by air from Mayotte to Reunion Island.This retrospective observational study evaluated all consecutive patients with ARF due to SARS-CoV-2 who were evacuated by air from Mayotte Hospital to the intensive care unit (ICU) of Félix Guyon University Hospital in Reunion Island between February 2, and March 5, 2021.A total of 43 patients with SARS-CoV-2 pneumonia were evacuated by air, for a total flight time of 2 hours and a total travel time of 6 hours. Of these, 38 patients (88.4%) with a median age of 55 (46-65) years presented with ARF and were hospitalized in our ICU. Fifteen patients were screened for the SARS-CoV-2 501Y.V2 variant, all of whom tested positive. Thirteen patients (34.2%) developed an episode of severe hypoxemia during air transport, and the median paO2/FiO2 ratio was lower on ICU admission (140 [102-192] mmHg) than on departure (165 [150-200], P = .022). Factors associated with severe hypoxemia during air transport was lack of treatment with curare (P = .012) and lack of invasive mechanical ventilation (P = .003). Nine patients (23.7%) received veno-venous extracorporeal membrane oxygenation support in our ICU. Seven deaths (18.4%) occurred in hospital.Emergency air evacuation of patients with ARF due to SARS-CoV-2 was associated with severe hypoxemia but remained feasible. In cases of ARF due to SARS-CoV-2 requiring emergency air evacuation, sedated patients receiving invasive mechanical ventilation and curare should be prioritized over nonintubated patients. It is noteworthy that patients with SARS-CoV-2 pneumonia related to the 501Y.V2 variant were very severe despite their young age.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Respiratory Distress Syndrome / Respiratory Insufficiency / Transportation of Patients / Air Ambulances / COVID-19 / Hypoxia Type of study: Diagnostic study / Experimental Studies / Observational study / Prognostic study Topics: Long Covid / Variants Limits: Aged / Humans / Middle aged Country/Region as subject: Africa Language: English Journal: Medicine (Baltimore) Year: 2021 Document Type: Article Affiliation country: MD.0000000000027881

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Respiratory Distress Syndrome / Respiratory Insufficiency / Transportation of Patients / Air Ambulances / COVID-19 / Hypoxia Type of study: Diagnostic study / Experimental Studies / Observational study / Prognostic study Topics: Long Covid / Variants Limits: Aged / Humans / Middle aged Country/Region as subject: Africa Language: English Journal: Medicine (Baltimore) Year: 2021 Document Type: Article Affiliation country: MD.0000000000027881