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"Just in Time": The Role of Cryo-Electron Microscopy in Combating Recent Pandemics.
Frank, Joachim.
  • Frank J; Department of Biochemistry and Molecular Biophysics, Columbia University, 650 West 168th Street, New York, New York 10032, United States.
Biochemistry ; 60(46): 3449-3451, 2021 11 23.
Article in English | MEDLINE | ID: covidwho-1590174
ABSTRACT
Single-particle cryogenic electron microscopy (cryo-EM), whose full power was not realized until the advent of powerful detectors in 2012, has a unique position as a method of structure determination as it is capable of providing information about not only the structure but also the dynamical features of biomolecules. This information is of special importance in understanding virus-host interaction and explains the crucial role of cryo-EM in the efforts to find vaccinations and cures for pandemics the world has experienced in the past decade.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Cryoelectron Microscopy / Single Molecule Imaging / Host Microbial Interactions Type of study: Observational study Topics: Vaccines Limits: Humans Language: English Journal: Biochemistry Year: 2021 Document Type: Article Affiliation country: Acs.biochem.1c00318

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Cryoelectron Microscopy / Single Molecule Imaging / Host Microbial Interactions Type of study: Observational study Topics: Vaccines Limits: Humans Language: English Journal: Biochemistry Year: 2021 Document Type: Article Affiliation country: Acs.biochem.1c00318