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Human papillomavirus vaccination in the European Union/European Economic Area and globally: a moral dilemma.
Colzani, Edoardo; Johansen, Kari; Johnson, Helen; Pastore Celentano, Lucia.
  • Colzani E; European Centre for Disease Prevention and Control, Stockholm, Sweden.
  • Johansen K; European Centre for Disease Prevention and Control, Stockholm, Sweden.
  • Johnson H; European Centre for Disease Prevention and Control, Stockholm, Sweden.
  • Pastore Celentano L; European Centre for Disease Prevention and Control, Stockholm, Sweden.
Euro Surveill ; 26(50)2021 Dec.
Article in English | MEDLINE | ID: covidwho-1631277
ABSTRACT
While many European Union/European Economic Area (EU/EEA) countries recently expanded human papillomavirus (HPV) vaccination to boys, HPV vaccine supply is currently limited for girls in low- and middle-income countries (LMIC) that are severely affected by HPV.Globally, about 50% of countries have introduced HPV vaccination. Some LMIC with high burden of cervical cancer have not yet introduced HPV vaccination, or are reaching suboptimal vaccination coverage. While WHO issued a call for cervical cancer elimination in 2018, a global shortage of HPV vaccines is currently predicted to last at least until 2024.We reviewed national policies of EU/EEA countries and recommendations of the World Health Organization (WHO) Strategic Advisory Group of Experts on immunisation to discuss current challenges and dose-sparing options. Several EU/EEA countries have extended HPV vaccination to boys and the European Cancer Organisation has issued a resolution for elimination of all HPV-associated cancers in both sexes. The European Centre for Disease Prevention and Control concluded in its 2020 guidance that cost-effectiveness of extending routine vaccination to boys depends on several context-specific factors. The extension of HPV vaccination to boys in EU/EEA countries may affect global availability of vaccines. Temporary dose-sparing options could be considered during the COVID-19 post-pandemic period.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Uterine Cervical Neoplasms / Papillomavirus Infections / Alphapapillomavirus / Papillomavirus Vaccines / COVID-19 Type of study: Prognostic study Topics: Vaccines Limits: Female / Humans / Male Language: English Journal subject: Communicable Diseases Year: 2021 Document Type: Article Affiliation country: 1560-7917.ES.2021.26.50.2001659

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Uterine Cervical Neoplasms / Papillomavirus Infections / Alphapapillomavirus / Papillomavirus Vaccines / COVID-19 Type of study: Prognostic study Topics: Vaccines Limits: Female / Humans / Male Language: English Journal subject: Communicable Diseases Year: 2021 Document Type: Article Affiliation country: 1560-7917.ES.2021.26.50.2001659