Platelet index in patients with confirmed coronavirus disease 2019 cases
Open Access Macedonian Journal of Medical Sciences
; 9:1705-1709, 2021.
Article
in English
| EMBASE | ID: covidwho-1593948
ABSTRACT
BACKGROUND:
Changes found on hematological examination are a helpful modality for assessing coronavirus disease 2019 (COVID-19). In addition, platelet index is a parameter that can help in assessing the COVID-19 disease prognosis.AIM:
Objective of the study is to determine the difference in platelet index in nucleid acid amplification test (NAAT) confirmed COVID-19 patients, suspected COVID-19 with negative NAAT results, and non-COVID-19 controls.METHODS:
This is an analytical observational study with 96 subjects;48 subjects with confirmed COVID-19, 23 subjects suspected COVID-19 with negative NAAT results, and 24 non-COVID-19 control subjects. First, NAAT examination was carried out using the GeneXpert tool with the target genes of the E and N2 genes. Then, the platelet index was compared between the three groups by the Kruskal-Wallis test.RESULTS:
There was no significant difference in the number of platelet (PLT), mean PLT volume (MPV), and PLT crit (PCT) between the three groups with p = 0.732, 0.741 and 0.483, respectively. In general, the number of PLT, MPV, and PCT in the three groups was within the normal reference value.CONCLUSIONS:
There were no significant differences observed in the number of PLT, MPV, and PCT between COVID-19 patients with positive NAAT, COVID-19 suspects with negative NAAT, and non-COVID-19 controls. Therefore, detecting the severe acute respiratory syndrome coronavirus 2 virus by NAAT examination in COVID-19 patients has not altered the PLT index changes.
adult; article; controlled, study; female; gene, amplification; human; human, cell; Kruskal, Wallis, test; major, clinical, study; male; mean, platelet, volume; nonhuman; observational, study; platelet, count; plateletcrit; polymerase, chain, reaction, system; reference, value; Severe, acute, respiratory, syndrome, coronavirus, 2
Full text:
Available
Collection:
Databases of international organizations
Database:
EMBASE
Language:
English
Journal:
Open Access Macedonian Journal of Medical Sciences
Year:
2021
Document Type:
Article
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