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A 67-Year-Old Male Patient With COVID-19 With Worsening Respiratory Function and Acute Kidney Failure.
Melchers, Max; Festen, Barbara; den Dekker, Bianca M; Mooren, Eline R M; van Binsbergen, Annelien L; van Bree, Sjoerd H W; Heusinkveld, Moniek; Schellaars, Roel; Buil, Jochem B; Verweij, Paul E; van Zanten, Arthur R H.
  • Melchers M; Department of Intensive Care Medicine, Hospital Gelderse Vallei, Ede, The Netherlands.
  • Festen B; Department of Intensive Care Medicine, Hospital Gelderse Vallei, Ede, The Netherlands.
  • den Dekker BM; Department of Intensive Care Medicine, Hospital Gelderse Vallei, Ede, The Netherlands.
  • Mooren ERM; Department of Intensive Care Medicine, Hospital Gelderse Vallei, Ede, The Netherlands.
  • van Binsbergen AL; Department of Intensive Care Medicine, Hospital Gelderse Vallei, Ede, The Netherlands.
  • van Bree SHW; Department of Intensive Care Medicine, Hospital Gelderse Vallei, Ede, The Netherlands.
  • Heusinkveld M; Department of Medical Microbiology, Hospital Gelderse Vallei, Ede, The Netherlands.
  • Schellaars R; Department of Intensive Care Medicine, Hospital Gelderse Vallei, Ede, The Netherlands.
  • Buil JB; Department of Medical Microbiology and Radboudumc-CWZ Center of Expertise for Mycology, Radboud University Medical Center, Nijmegen, The Netherlands.
  • Verweij PE; Department of Medical Microbiology and Radboudumc-CWZ Center of Expertise for Mycology, Radboud University Medical Center, Nijmegen, The Netherlands.
  • van Zanten ARH; Department of Intensive Care Medicine, Hospital Gelderse Vallei, Ede, The Netherlands; Division of Human Nutrition and Health, Wageningen University & Research, Wageningen, The Netherlands. Electronic address: zantena@zgv.nl.
Chest ; 161(1): e5-e11, 2022 01.
Article in English | MEDLINE | ID: covidwho-1595933
ABSTRACT
CASE PRESENTATION A 67-year-old obese man (BMI 38.0) with type 2 diabetes mellitus (DM), chronic atrial fibrillation, and chronic lymphocytic leukemia stage II, stable for 8 years after chemotherapy, and a history of smoking presented to the ED with progressive dyspnea and fever due to SARS-CoV-2 infection. He was admitted to a general ward and treated with dexamethasone (6 mg IV once daily) and oxygen. On day 3 of hospital admission, he became progressively hypoxemic and was admitted to the ICU for invasive mechanical ventilation. Dexamethasone treatment was continued, and a single dose of tocilizumab (800 mg) was administered. On day 9 of ICU admission, voriconazole treatment was initiated after tracheal white plaques at bronchoscopy, suggestive of invasive Aspergillus tracheobronchitis, were noticed. However, his medical situation dramatically deteriorated.
Subject(s)

Full text: Available Collection: International databases Database: MEDLINE Main subject: Pulmonary Aspergillosis / Acute Kidney Injury / COVID-19 / Mucormycosis / Antifungal Agents Type of study: Case report Limits: Aged / Humans / Male Language: English Journal: Chest Year: 2022 Document Type: Article Affiliation country: J.chest.2021.08.045

Full text: Available Collection: International databases Database: MEDLINE Main subject: Pulmonary Aspergillosis / Acute Kidney Injury / COVID-19 / Mucormycosis / Antifungal Agents Type of study: Case report Limits: Aged / Humans / Male Language: English Journal: Chest Year: 2022 Document Type: Article Affiliation country: J.chest.2021.08.045