Adult-onset Still's Disease after BNT162b2 mRNA COVID-19 Vaccine.
J Korean Med Sci
; 36(50): e344, 2021 Dec 27.
Article
in English
| MEDLINE | ID: covidwho-1596795
ABSTRACT
The coronavirus disease 2019 (COVID-19) pandemic is being overcome by widespread inoculation with various COVID-19 vaccines, but concerns about the safety of the vaccines are a major hurdle to widespread vaccination. We report the first case of adult-onset Still's disease (AOSD) developing in a 36-year-old, previously healthy woman after the first dose of BNT162b2 mRNA COVID-19 vaccine (Pfizer). She visited our hospital due to high spiking fever and sore throat that developed 10 days after vaccination. Based on thorough investigations and changes in symptoms and signs after admission, she was diagnosed with AOSD and treated with high dose steroids and tocilizumab. This report suggests the possibility that AOSD could be triggered by COVID-19 vaccines through activation of the innate immune system.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Vaccination
/
Still's Disease, Adult-Onset
/
BNT162 Vaccine
Type of study:
Case report
Topics:
Vaccines
Limits:
Adult
/
Female
/
Humans
Language:
English
Journal:
J Korean Med Sci
Journal subject:
Medicine
Year:
2021
Document Type:
Article
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