Emerging Phospholipid Nanobiomaterials for Biomedical Applications to Lab-on-a-Chip, Drug Delivery, and Cellular Engineering.
ACS Appl Bio Mater
; 4(12): 8110-8128, 2021 12 20.
Article
in English
| MEDLINE | ID: covidwho-1597218
ABSTRACT
The design of advanced nanobiomaterials to improve analytical accuracy and therapeutic efficacy has become an important prerequisite for the development of innovative nanomedicines. Recently, phospholipid nanobiomaterials including 2-methacryloyloxyethyl phosphorylcholine (MPC) have attracted great attention with remarkable characteristics such as resistance to nonspecific protein adsorption and cell adhesion for various biomedical applications. Despite many recent reports, there is a lack of comprehensive review on the phospholipid nanobiomaterials from synthesis to diagnostic and therapeutic applications. Here, we review the synthesis and characterization of phospholipid nanobiomaterials focusing on MPC polymers and highlight their attractive potentials for applications in micro/nanofabricated fluidic devices, biosensors, lab-on-a-chip, drug delivery systems (DDSs), COVID-19 potential usages for early diagnosis and even treatment, and artificial extracellular matrix scaffolds for cellular engineering.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Phospholipids
/
Biocompatible Materials
/
Drug Carriers
/
Nanostructures
/
Lab-On-A-Chip Devices
Type of study:
Diagnostic study
Limits:
Humans
Language:
English
Journal:
ACS Appl Bio Mater
Year:
2021
Document Type:
Article
Affiliation country:
Acsabm.1c00932
Similar
MEDLINE
...
LILACS
LIS