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FACTORS RELATED TO NEW ONSET DYSPEPSIA AFTER COVID 19 INFECTION IN MEXICAN POPULATION
Gastroenterology ; 160(6):S-191, 2021.
Article in English | EMBASE | ID: covidwho-1597396
ABSTRACT
ntroduction Since the COVID 19 infection has been declared a pandemic by the World Health Organization, the spectrum of symptoms have been described, however, the presence of digestive symptoms as part of the probable sequelae of the disease has not been well studied.

Objective:

To determine the variables present during the active stage period of the COVID 19 infection and their association with symptoms of dyspepsia during the recovery period. Material and

methods:

An online survey was conducted to patients recovered from COVID 19 infection during the months of May and June 2020, evaluating the demographic variables of age, sex and comorbidities, the presence of COVID 19 infection symptoms during the disease active stage and digestive symptoms during recovery. Using SPSS version 22, univar-iate and multivariate logistic regression analysis was performed to determine the variables associated with the presence of dyspeptic symptoms such as early satiety, epigastric pain and postprandial fullness during recovery from the disease (4 weeks after the infection resolved).

Results:

A total of 315 patients recovered from COVID 19 infection were evaluated, mainly 59.6% from Baja California, 12.2% from Sonora, 7.8% CDMX, 6% Sinaloa, 3% Veracruz with an average age of 35.7 ±11.5 years of age, 65.4% female, with obesity comorbidities in 19.6% of cases, high blood pressure in 10.9%, asthma in 7.1% and diabetes mellitus in 2.2%. The most frequent symptoms reported of the disease were headache 79.5 %, myalgias 64.1%, diarrhea 60.9%, anosmia 62.2%, fever 57.1%, ageusia 58.7%, odynophagia 56.1%, arthralgias 54.7%, anorexia 52.6%, cough 49.7%, chest pain 39.4%, dyspnea 28.5%. Dyspep-sia in the recovery period was reported with pain in 18.6%, postprandial fullness 34.3%and early satiety in 52.2%. It was found that the variables independently associated with the presence of postprandial fullness during recovery from the disease are male (OR 0.544,IC 0.309-0.958, P = 0.035), anorexia (OR 3.07, IC 1.73-5.45, P <.001) and diarrhea (OR 1.87. IC 1.04-3.34, P = 0.034). The variable associated with the presence of satiety during recovery from the disease is the presence of anorexia (OR 6.65, CI 3.75-11.79, P <0.001). The presence of epigastric pain after COVID 19 infection is associated with diarrhea (OR 3.32, IC 1.42-7.79, P = 0.006), arthralgia (OR 3.15, IC 3.15-1.16-8.55, P = 0.026), treatment with azithromycin ( OR 2.29, IC 1.13-4.64, P = 0.021), chlorine dioxide treatment (OR 11.35, IC 2.69-47.9, P = 0.001).

Conclusions:

The presence of dyspepsia after infection by COVID 19 is frequent, some of the associated variables are similar to those reported in other cases of post-infectious dyspep-sia, the use of medications has an important relationship with the presence of epigastric pain.
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Full text: Available Collection: Databases of international organizations Database: EMBASE Country/Region as subject: Mexico Language: English Journal: Gastroenterology Year: 2021 Document Type: Article

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Full text: Available Collection: Databases of international organizations Database: EMBASE Country/Region as subject: Mexico Language: English Journal: Gastroenterology Year: 2021 Document Type: Article