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Fear Of Covid-19, Along With Stress, Anxiety, And Depression, Is Associated With Biologic Usage In Patients With Inflammatory Bowel Disease
Gastroenterology ; 160(6):S-335, 2021.
Article in English | EMBASE | ID: covidwho-1597949
ABSTRACT

Background:

During The Covid-19 Pandemic, The General Population Has Been Subject To Heightened Stress, Anxiety, Depression, And Fear Of The Virus. However, The Impact Of Covid-19 On These Psychometric Factors Have Not Been Formally Assessed In Patients With Inflammatory Bowel Disease (Ibd), Specifically Those On Biologic Therapies. The Aim Of This Study Was To Examine The Relationship Between Fear Of Covid-19 And Biologic Usage In Ibd Patients.

Methods:

Adult Ibd And Non-Ibd Patients Were Recruited From An Academic Clinic And Via Social Media Outlets. Patients Were Administered A Qualtrics Survey Assessing Demographics Disease Characteristics, And Perceptions Around Covid-19. The Validated Fear Of Covid-19 Scale (Fcv-19s), Perceived Stress Scale (Pss), And Hospital Anxiety And Depression Scale (Hads) Were Used To Assess Fear Of Covid-19, Stress, Anxiety And Depression, Respectively. Analyses Evaluated The Associations Between These Psychological Experiences, Ibd Diagnosis, And Medication Usage.

Results:

There Were 399 Participants (17% Crohn’S Disease;43% Ulcerative Colitis;4% Ibd-Unclassified;36% Non-Ibd). Ibd Participants Had Higher Levels Of Stress (P<.01), Anxiety (P<.01), Depression (P<.01), And Fear Of Covid-19 (P<.01) Compared With Non-Ibd Participants. When Asked About Perceived Likelihood Of Contracting Covid-19, Ibd Participants More Often Responded With A “High” Or “Extreme” Likelihood (26.3% Vs. 9.1%;P<.01). Among The Risk Perception Screening Domains, 77.9% And 45.9% Of Ibd Participants On Biologics Responded “Very” Or “Extremely” Affirmatively To Questions Related To Perceived Level Of Precaution Needed To Avoid Contracting Covid-19 And Perceived Severity Of Infection If Contracted, Respectively. Additionally, 41.5% Of Ibd Participants On Biologics Were More Likely To Report Feeling That Their Ibd Medications Made Them “Extremely” Or “Very” Vulnerable, Compared With Only 20.3% Of Ibd Participants Not On Biologic Therapy. Use Of Biologic Therapy Was Associated With Higher Levels Of Stress (P=.011), Anxiety (P<.01), And Fear Of Covid-19 (P<.01). Due To Concerns Of Covid-19, 5.6% Decided To Defer Starting Biologic Treatment, While 2.0% Decided To Discontinue Biologic Medication.

Conclusion:

This Study Is One Of The First To Evaluate The Mental Health Of Ibd Patients During The Covid-19 Pandemic And Uniquely Evaluates Psychological Variables As They Relate To Biologic Usage. Fear Of Covid-19, Anxiety, And Perceived Stress Were Strongly Correlated With Biologic Usage In Ibd Patients, Suggesting That Participants Using Biologic Therapy Felt More Susceptible To Infection. Furthermore, These Findings Have Implications On Patient Adherence To Immunosuppressive Medications During The Covid-19 Pandemic, Which Should Be Considered During Therapy-Related Discussions Between Physicians And Ibd Patients (Table Presented)
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Full text: Available Collection: Databases of international organizations Database: EMBASE Language: English Journal: Gastroenterology Year: 2021 Document Type: Article

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Full text: Available Collection: Databases of international organizations Database: EMBASE Language: English Journal: Gastroenterology Year: 2021 Document Type: Article