The Incubation Period Distribution of Coronavirus Disease 2019: A Systematic Review and Meta-analysis.
Clin Infect Dis
; 73(12): 2344-2352, 2021 12 16.
Article
in English
| MEDLINE | ID: covidwho-1599313
ABSTRACT
Incubation period is an important parameter to inform quarantine period and to study transmission dynamics of infectious diseases. We conducted a systematic review and meta-analysis on published estimates of the incubation period distribution of coronavirus disease 2019, and showed that the pooled median of the point estimates of the mean, median and 95th percentile for incubation period are 6.3 days (range, 1.8-11.9 days), 5.4 days (range, 2.0-17.9 days), and 13.1 days (range, 3.2-17.8 days), respectively. Estimates of the mean and 95th percentile of the incubation period distribution were considerably shorter before the epidemic peak in China compared to after the peak, and variation was also noticed for different choices of methodological approach in estimation. Our findings implied that corrections may be needed before directly applying estimates of incubation period into control of or further studies on emerging infectious diseases.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Communicable Diseases, Emerging
/
Infectious Disease Incubation Period
/
COVID-19
Type of study:
Observational study
/
Reviews
/
Systematic review/Meta Analysis
Limits:
Humans
Country/Region as subject:
Asia
Language:
English
Journal:
Clin Infect Dis
Journal subject:
Communicable Diseases
Year:
2021
Document Type:
Article
Affiliation country:
Cid
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