Impact of COVID-19 on in-hospital cardiac arrest outcomes: An updated meta-analysis.
Cardiol J
; 28(6): 816-824, 2021.
Article
in English
| MEDLINE | ID: covidwho-1603899
ABSTRACT
BACKGROUND:
The main purposes of this meta-analysis are to update the information about the impact of coronavirus disease 2019 (COVID-19) pandemic on outcomes of in-hospital cardiac arrest (IHCA) and to investigate the impact of being infected by by severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) on IHCA outcomes.METHODS:
The current meta-analysis is an update and follows the recommendations of Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA).RESULTS:
In analyses, pre- and intra-COVID-19 periods were observed for shockable rhythms in 17.6% vs. 16.2% (odds ratio [OR] 1.11; 95% confidence interval [CI] 0.71-1.72; p = 0.65), return of spontaneous circulation (ROSC) in 47.4% vs. 44.0% (OR 1.36; 95% CI 0.90-2.07; p = 0.15), 30-day mortality in 59.8% vs. 60.9% (OR 0.95; 95% CI 0.75-1.22; p = 0.69) and overall mortality 75.8% vs. 74.7% (OR 0.80; 95% CI 0.49-1.28; p = 0.35), respectively. In analyses, SARS-CoV-2 positive and negative patients were observed for shockable rhythms in 9.6% vs. 19.8% (OR 0.51; 95% CI 0.35-0.73; p < 0.001), ROSC in 33.9% vs. 52.1% (OR 0.47; 95% CI 0.30-0.73; p < 0.001), 30-day mortality in 77.2% vs. 59.7% (OR 2.08; 95% CI 1.28-3.38; p = 0.003) and overall mortality in 94.9% vs. 76.7% (OR 3.20; 95% CI 0.98-10.49; p = 0.05), respectively.CONCLUSIONS:
Despite ROSC, 30-day and overall mortality rate were not statistically different in pre- vs. intra-COVID-19 periods, a lower incidence of ROSC and higher 20-day mortality rate were observed in SARS-CoV-2 (+) compared to SARS-CoV-2 (-) patients.Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Cardiopulmonary Resuscitation
/
COVID-19
/
Heart Arrest
Type of study:
Experimental Studies
/
Observational study
/
Prognostic study
/
Reviews
/
Systematic review/Meta Analysis
Limits:
Humans
Language:
English
Journal:
Cardiol J
Year:
2021
Document Type:
Article
Affiliation country:
CJ.a2021.0168
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