Post coronavirus disease-2019 vaccination Guillain-Barré syndrome.
Indian J Public Health
; 65(4): 422-424, 2021.
Article
in English
| MEDLINE | ID: covidwho-1603912
ABSTRACT
Guillain-Barré syndrome (GBS) is an acute inflammatory demyelinating disorder of the peripheral nerve. Different variants of GBS can produce a wide array of symptoms among which motor weakness, areflexia without bladder-bowel involvement are commonly encountered. ChAdOx1 nCoV-19 is a recombinant Corona Virus Vaccine and it is incorporated into India's coronavirus disease-2019 (COVID-19) vaccination program. Few rare instances of serious neurological complications have been reported following COVID-19 vaccination. Our case received 2 dose of COVID-19 vaccine. After receiving 1st dose he had rapid onset of ascending paralysis without any sensory and bladder bowel involvement. He received Intra Venous Immuno Globulin and Injection prednisolone for 5 days. Following that his lower limb weakness resolved rapidly but there was no improvement in upper limb weakness. Nerve conduction study showed demyelinating etiology and along with clinical features, it was appeared to be a case of GBS. However, more evidence is needed before establishing the causal relationship between COVID-19 vaccines and GBS.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Guillain-Barre Syndrome
/
COVID-19
Type of study:
Case report
/
Etiology study
/
Prognostic study
Topics:
Vaccines
/
Variants
Limits:
Humans
/
Male
Country/Region as subject:
Asia
Language:
English
Journal:
Indian J Public Health
Year:
2021
Document Type:
Article
Affiliation country:
Ijph.ijph_1716_21
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