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Bilateral Neonatal Adrenal Hemorrhage Associated With Severe Maternal COVID-19 Infection.
Concepción-Zavaleta, Marcio José; Ildefonso-Najarro, Sofia Pilar; Plasencia-Dueñas, Esteban; Coronado Arroyo, Julia Cristina; Zavaleta-Gutiérrez, Francisca Elena; Concepción-Urteaga, Luis; Massucco Revoredo, Frederick; Ramos-Yataco, Anthony; Meza, Kelly.
  • Concepción-Zavaleta MJ; Endocrinology, Clínica Stella Maris, Lima, PER.
  • Ildefonso-Najarro SP; Endocrinology, Diabetes and Metabolism, Hospital Nacional Guillermo Almenara, Lima, PER.
  • Plasencia-Dueñas E; Endocrinology, Diabetes and Metabolism, Hospital Nacional Guillermo Almenara, Lima, PER.
  • Coronado Arroyo JC; Obstetrics and Gynecology, Clínica Vesalio, Lima, PER.
  • Zavaleta-Gutiérrez FE; Pediatrics and Neonatology, Hospital Belén de Trujillo, Trujillo, PER.
  • Concepción-Urteaga L; Internal Medicine, Hospital Regional Docente de Trujillo, Trujillo, PER.
  • Massucco Revoredo F; Endocrinology, Hospital Nacional Guillermo Almenara Irigoyen, Lima, PER.
  • Ramos-Yataco A; Internal Medicine, Hospital Ricardo Cruzado Rivarola, Nasca, PER.
  • Meza K; Pediatric Nephrology, Weill Cornell Medicine, New York, USA.
Cureus ; 13(11): e20007, 2021 Nov.
Article in English | MEDLINE | ID: covidwho-1604368
ABSTRACT
Adrenal hemorrhage is the most common cause of adrenal mass in newborns. We present a case of a full-term male, born by cesarean section due to acute fetal distress from a mother with severe coronavirus disease 2019 (COVID-19) infection. He was diagnosed with hypoxic-ischemic encephalopathy, multifactorial shock, and early neonatal sepsis. On the seventh day of hospitalization, hemoglobin dropped and thus blood transfusion was required, and abdominal ultrasound showed bilateral adrenal hemorrhage. He developed relative adrenal insufficiency without either hemodynamic instability or electrolyte imbalances. The use of parenteral corticosteroids was not required. Follow-up ultrasonography and adrenal axis laboratory examination revealed complete resolution of adrenal hemorrhage. Neonatal adrenal hemorrhage has a wide variety of clinical manifestations. Ultrasound is preferred for both initial screening and follow-up evaluation. Adrenal insufficiency occurs rarely in neonatal adrenal hemorrhage. Treatment is usually conservative. We emphasize the importance of a timely diagnosis and clinical follow-up of adrenal hemorrhage in neonates with fetal distress born from mothers with severe COVID-19.
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Full text: Available Collection: International databases Database: MEDLINE Type of study: Risk factors Language: English Journal: Cureus Year: 2021 Document Type: Article

Full text: Available Collection: International databases Database: MEDLINE Type of study: Risk factors Language: English Journal: Cureus Year: 2021 Document Type: Article