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First Reported Case of Reversible Cerebral Vasoconstriction Syndrome After a SARS-CoV-2 Vaccine.
Finsterer, Josef.
  • Finsterer J; Neurology, Krankenanstalt Rudolfstiftung, Vienna, AUT.
Cureus ; 13(11): e19987, 2021 Nov.
Article in English | MEDLINE | ID: covidwho-1604842
ABSTRACT
This is the first report of reversible cerebral vasoconstriction syndrome (RCVS) as a complication of a SARS-CoV-2 vaccination. A 38-year-old female developed visual impairment due to scotomas and thunderclap headache 18 days after the second shot of the Moderna SARS-CoV-2 vaccine. Multimodal cerebral MRI revealed an acute cortical ischemic lesion in the territory of the right posterior cerebral artery (PCA) on T2-weighted images, diffusion-weighted imaging (DWI), apparent diffusion coefficient (ADC) maps and absence of the PCA on magnetic resonance angiography (MRA). RCVS was diagnosed as the cause of the ischemic lesion. RCVS partially resolved upon nimodipine and anti-seizure drugs within nine days. In conclusion, this case shows that a SARS-CoV-2 vaccination can be followed by RCVS, manifesting as headache, stroke, and epileptiform discharges, and responding favorably to nimodipine.
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Full text: Available Collection: International databases Database: MEDLINE Type of study: Case report Language: English Journal: Cureus Year: 2021 Document Type: Article

Full text: Available Collection: International databases Database: MEDLINE Type of study: Case report Language: English Journal: Cureus Year: 2021 Document Type: Article