Acute worsening of native lung fibrosis after single lung transplantation for pulmonary fibrosis: two case reports.
J Med Case Rep
; 16(1): 2, 2022 Jan 03.
Article
in English
| MEDLINE | ID: covidwho-1605063
ABSTRACT
BACKGROUND:
In patients receiving single lung transplantation for idiopathic pulmonary fibrosis, worsening of fibrosis of the native lung is usually progressive over time, with no significant effects on gas exchange. CASE PRESENTATION Here, we describe the cases of two Caucasian male recipients of single lung transplants for idiopathic pulmonary fibrosis, 65 and 62 years of age, who exhibited acute worsening of lung fibrosis after an episode of serious viral infection (cytomegalovirus primo-infection in one case and COVID-19 in the other). In both cases, along with opacification of the native lung over several days, the patients presented acute respiratory failure that required the use of high-flow nasal oxygen therapy. Eventually, hypoxemic respiratory failure resolved, but with rapid progression of fibrosis of the native lung.CONCLUSION:
We conclude that acute worsening of fibrosis on the native lung secondary to a severe viral infection should be added to the list of potential complications developing on the native lung after single lung transplantation for idiopathic pulmonary fibrosis.Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Lung Transplantation
/
Idiopathic Pulmonary Fibrosis
/
COVID-19
Type of study:
Case report
Limits:
Humans
/
Male
Language:
English
Journal:
J Med Case Rep
Year:
2022
Document Type:
Article
Affiliation country:
S13256-021-03191-9
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