COVID-19: an In Silico Analysis on Potential Therapeutic Uses of Trikadu as Immune System Boosters.
Appl Biochem Biotechnol
; 194(1): 291-301, 2022 Jan.
Article
in English
| MEDLINE | ID: covidwho-1748423
ABSTRACT
Corona virus pandemic outbreak also known as COVID-19 has created an imbalance in this world. Scientists have adopted the use of natural or alternative medicines which are consumed mostly as dietary supplements to boost the immune system as herbal remedies. India is famous for traditional medicinal formulations which includes 'Trikadu'-a combination of three acrids, namely Zingiber officinale, Piper nigrum and Piper longum which have antioxidant properties that boost our immune system hence acting as a strong preventive measure. In this study, AutoDock 4.0 was used to study interaction between the phytocompounds of Trikadu with RNA-dependent polymerase protein and enveloped protein of the SARS-CoV-2 virus. Analysis of the results showed that coumarin, coumaperine and bisdemethoxycurcumin showed strong bonding interactions with both the proteins. We can conclude that Trikadu has the potential molecules; hence, it can be incorporated in the diet to boost the immune system as a preventive measure against the virus.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Plant Preparations
/
SARS-CoV-2
/
COVID-19
/
COVID-19 Drug Treatment
/
Phytotherapy
Topics:
Traditional medicine
/
Vaccines
Limits:
Humans
Country/Region as subject:
Asia
Language:
English
Journal:
Appl Biochem Biotechnol
Year:
2022
Document Type:
Article
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