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COVID-19 mRNA Vaccine-induced Pneumonitis.
Matsuzaki, Shinichi; Kamiya, Hiroyuki; Inoshima, Ichiro; Hirasawa, Yasutaka; Tago, Osamu; Arai, Masashi.
  • Matsuzaki S; Department of Respiratory Medicine, Tatebayashi Kosei General Hospital, Japan.
  • Kamiya H; Department of Respiratory Medicine, Tatebayashi Kosei General Hospital, Japan.
  • Inoshima I; Department of Respiratory Medicine, Tatebayashi Kosei General Hospital, Japan.
  • Hirasawa Y; Department of Pulmonology, International University of Health and Welfare, Japan.
  • Tago O; Department of Dermatology, Tatebayashi Kosei General Hospital, Japan.
  • Arai M; Department of Internal Medicine, Tatebayashi Kosei General Hospital, Japan.
Intern Med ; 61(1): 81-86, 2022 Jan 01.
Article in English | MEDLINE | ID: covidwho-1606476
ABSTRACT
A 65-year-old man experienced cough and shortness of breath 3 days after receiving the first dose of the Pfizer-BioNTech coronavirus disease 2019 (COVID-19) vaccine. Chest X-ray revealed bilateral infiltrates, and the desaturation deteriorated rapidly. The symptoms and radiographic abnormalities rapidly improved after the initiation of corticosteroid therapy. Intradermal testing of the Pfizer-BioNTech COVID-19 vaccine showed a delayed positive reaction. Based on these findings, the patient was diagnosed with COVID-19 vaccine-induced pneumonitis. The timing of the onset of pneumonitis after vaccination and the results of intradermal testing suggest that Type IV hypersensitivity against COVID-19 vaccine may have been responsible for this clinical condition.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Vaccines / COVID-19 Type of study: Case report / Prognostic study Topics: Vaccines Limits: Aged / Humans / Male Language: English Journal: Intern Med Journal subject: Internal Medicine Year: 2022 Document Type: Article Affiliation country: Internalmedicine.8310-21

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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Vaccines / COVID-19 Type of study: Case report / Prognostic study Topics: Vaccines Limits: Aged / Humans / Male Language: English Journal: Intern Med Journal subject: Internal Medicine Year: 2022 Document Type: Article Affiliation country: Internalmedicine.8310-21