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COVID-19 Infection in Pregnancy: A Review.
Mily, Sabrina Jahan; Akter, Kazi Mahmuda; Jabin, Nowshin; Mitra, Saikat; Emran, Talha Bin; Nandi, Monisha; Baral, Sumit Kumar; Uddin, Md Zia; Mallick, Jewel; Paul, Arkajyoti; Shah, Syed Uzair Ali; Rauf, Abdur; Khan, Ishaq N; Mubarak, Mohammad S.
  • Mily SJ; Department of Gynaecology and Obstetrics, Banshkhali Upazila Health Complex, Jaldi Union, Chittagong 4390, Bangladesh.
  • Akter KM; Department of Obstetrics and Gynaecology, Sir Salimullah Medical College Mitford Hospital, Dhaka 1100, Bangladesh.
  • Jabin N; Center for Biomedical Research and Training, M4Y 1R6, Ontario, Toronto, Canada.
  • Mitra S; Department of Obstetrics and Gynaecology, Chittagong Medical College, Chittagong 4203, Bangladesh.
  • Emran TB; Department of Pharmacy, Faculty of Pharmacy, University of Dhaka, Dhaka 1000, Bangladesh.
  • Nandi M; Department of Pharmacy, BGC Trust University Bangladesh, Chittagong 4381, Bangladesh.
  • Baral SK; Department of Pharmacy, BGC Trust University Bangladesh, Chittagong 4381, Bangladesh.
  • Uddin MZ; Department of Microbiology, Jagannath University, Dhaka 1100, Bangladesh.
  • Mallick J; Department of Pharmacy, BGC Trust University Bangladesh, Chittagong 4381, Bangladesh.
  • Paul A; Department of Pharmacy, BGC Trust University Bangladesh, Chittagong 4381, Bangladesh.
  • Shah SUA; Department of Pharmacy, BGC Trust University Bangladesh, Chittagong 4381, Bangladesh.
  • Rauf A; Department of Microbiology, Jagannath University, Dhaka 1100, Bangladesh.
  • Khan IN; Drug Discovery, GUSTO A Research Group, Chittagong 4000, Bangladesh.
  • Mubarak MS; Department of Pharmacy, University of Swabi, Swabi, K.P. Pakistan.
Infect Disord Drug Targets ; 22(5): 12-21, 2022.
Article in English | MEDLINE | ID: covidwho-1606600
ABSTRACT
Coronavirus disease 2019 (COVID-19), which is a highly contagious viral illness caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has had a catastrophic effect on the world's demographics, resulting in more than 3.8 million deaths worldwide and establishing itself as the most serious global health crisis since the 1918 influenza pandemic. Several questions remain unanswered regarding the effects of COVID-19 disease during pregnancy. Although most infections are mild in high-risk populations, the severe disease frequently leads to intubation, intensive care unit admission, and, in some cases, death. Hormonal and physiological changes in the immune and respiratory systems, cardiovascular function, and coagulation may affect the progression of COVID-19 disease in pregnancy. However, the consequences of coronavirus infection on implantation, fetal growth and development, labor, and newborn health have yet to be determined, and, consequently, a coordinated global effort is needed in this respect. Principles of management concerning COVID-19 in pregnancy include early isolation, aggressive infection control procedures, oxygen therapy, avoidance of fluid overload, consideration of empiric antibiotics (secondary to bacterial infection risk), laboratory testing for the virus and co-infection, fetal and uterine contraction monitoring, prevention, and / or treatment of thromboembolism early mechanical ventilation for progressive respiratory failure, individualized delivery planning, and a team-based approach with multispecialty consultations. This review focuses on COVID-19 during pregnancy, its management, and the area where further investigations are needed to reduce the risk to mothers and their newborns.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pregnancy Complications, Infectious / COVID-19 Type of study: Observational study / Prognostic study Limits: Female / Humans / Infant, Newborn / Pregnancy Language: English Journal: Infect Disord Drug Targets Journal subject: Communicable Diseases / Drug Therapy Year: 2022 Document Type: Article Affiliation country: 1871526522666220105111358

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pregnancy Complications, Infectious / COVID-19 Type of study: Observational study / Prognostic study Limits: Female / Humans / Infant, Newborn / Pregnancy Language: English Journal: Infect Disord Drug Targets Journal subject: Communicable Diseases / Drug Therapy Year: 2022 Document Type: Article Affiliation country: 1871526522666220105111358