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SARS-CoV-2 Omicron RBD shows weaker binding affinity than the currently dominant Delta variant to human ACE2.
Wu, Leyun; Zhou, Liping; Mo, Mengxia; Liu, Tingting; Wu, Chengkun; Gong, Chunye; Lu, Kai; Gong, Likun; Zhu, Weiliang; Xu, Zhijian.
  • Wu L; CAS Key Laboratory of Receptor Research, Drug Discovery and Design Center, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.
  • Zhou L; CAS Key Laboratory of Receptor Research, Drug Discovery and Design Center, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.
  • Mo M; College of Computer Science and Technology, National University of Defense Technology, Changsha, 410073, China.
  • Liu T; Center for Drug Safety Evaluation and Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.
  • Wu C; College of Computer Science and Technology, National University of Defense Technology, Changsha, 410073, China.
  • Gong C; College of Computer Science and Technology, National University of Defense Technology, Changsha, 410073, China.
  • Lu K; College of Computer Science and Technology, National University of Defense Technology, Changsha, 410073, China.
  • Gong L; Center for Drug Safety Evaluation and Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China. lkgong@cdser.simm.ac.cn.
  • Zhu W; CAS Key Laboratory of Receptor Research, Drug Discovery and Design Center, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China. wlzhu@simm.ac.cn.
  • Xu Z; CAS Key Laboratory of Receptor Research, Drug Discovery and Design Center, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China. zjxu@simm.ac.cn.
Signal Transduct Target Ther ; 7(1): 8, 2022 01 05.
Article in English | MEDLINE | ID: covidwho-1608673
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Full text: Available Collection: International databases Database: MEDLINE Main subject: SARS-CoV-2 / COVID-19 Topics: Variants Limits: Humans Language: English Journal: Signal Transduct Target Ther Year: 2022 Document Type: Article Affiliation country: S41392-021-00863-2

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Full text: Available Collection: International databases Database: MEDLINE Main subject: SARS-CoV-2 / COVID-19 Topics: Variants Limits: Humans Language: English Journal: Signal Transduct Target Ther Year: 2022 Document Type: Article Affiliation country: S41392-021-00863-2