[Pathogenic mechanisms of SARS-CoV-2 infection and kidney disease: a clinical and molecular perspective].
An Sist Sanit Navar
; 44(3): 445-456, 2021 Dec 27.
Article
in Spanish
| MEDLINE | ID: covidwho-1609080
ABSTRACT
The SARS-CoV-2 infection has become as a worldwide public health emergency. It exhibits a variety of clinical presentations, ranging from benign to acute respiratory distress syndrome, systemic involvement, and multiorganic failure. The severity of the clinical picture depends on host and virus biological features and the presence of comorbidities such as chronic kidney disease. In addition, the interaction between the virus, angiotensin-converting enzyme 2, and the exacerbated immune response could lead to the development of acute kidney injury. However, the implications of SARS-CoV-2 infection on renal cells, the prognosis of patients with chronic kidney disease, and the long-term behavior of renal function are not entirely understood. This review aims to explore the role of SARS-CoV-2 in acute and chronic kidney disease and the possible pathogenic mechanisms of renal involvement.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Renal Insufficiency, Chronic
/
Acute Kidney Injury
/
COVID-19
Type of study:
Prognostic study
Limits:
Humans
Language:
Spanish
Journal:
An Sist Sanit Navar
Journal subject:
Public Health
Year:
2021
Document Type:
Article
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