Neuropsychiatric syndrome with myoclonus after SARS-CoV-2 infection in a paediatric patient.
Clin Neurol Neurosurg
; 213: 107121, 2022 02.
Article
in English
| MEDLINE | ID: covidwho-1611660
ABSTRACT
We report the case of a 12-years-old patient who subacutely developed a positive and negative myoclonus of limbs and face, drowsiness and memory deficits after getting infected by SARS-CoV-2. On admission, nasopharyngeal swab for SARS-CoV-2, brain and spinal MRI with and without contrast, EEG, chest X-ray and abdominal ultrasound were negative. CSF physical-chemical examination, culture, PCR testing for SARS-CoV-2 and other pathogens, and oligoclonal IgG bands were negative as well. A full panel blood test, including clotting, autoimmunity and paraneoplastic blood studies, did not show any alteration. The neuropsychological examination showed an impairment in memory, visual-motor coordination, inductive reasoning skills, attention, and concentration. The patient was first treated with clonazepam and then with intravenous methylprednisolone for five days, with poor response. For this reason, he then received a cycle of IVIG, thus reaching a gradual and complete recovery. To date, this is the first case of a COVID-19 associated myoclonus affecting a paediatric patient.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
COVID-19
/
Mental Disorders
/
Myoclonus
Type of study:
Case report
/
Diagnostic study
/
Observational study
Topics:
Long Covid
Limits:
Child
/
Humans
/
Male
Language:
English
Journal:
Clin Neurol Neurosurg
Year:
2022
Document Type:
Article
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