Obesity as a mortality risk factor in the medical ward: a case control study.
BMC Endocr Disord
; 22(1): 13, 2022 Jan 06.
Article
in English
| MEDLINE | ID: covidwho-1613234
ABSTRACT
BACKGROUND:
Research regarding the association between severe obesity and in-hospital mortality is inconsistent. We evaluated the impact of body mass index (BMI) levels on mortality in the medical wards. The analysis was performed separately before and during the COVID-19 pandemic.METHODS:
We retrospectively retrieved data of adult patients admitted to the medical wards at the Mount Sinai Health System in New York City. The study was conducted between January 1, 2011, to March 23, 2021. Patients were divided into two sub-cohorts pre-COVID-19 and during-COVID-19. Patients were then clustered into groups based on BMI ranges. A multivariate logistic regression analysis compared the mortality rate among the BMI groups, before and during the pandemic.RESULTS:
Overall, 179,288 patients were admitted to the medical wards and had a recorded BMI measurement. 149,098 were admitted before the COVID-19 pandemic and 30,190 during the pandemic. Pre-pandemic, multivariate analysis showed a "J curve" between BMI and mortality. Severe obesity (BMI > 40) had an aOR of 0.8 (95% CI0.7-1.0, p = 0.018) compared to the normal BMI group. In contrast, during the pandemic, the analysis showed a "U curve" between BMI and mortality. Severe obesity had an aOR of 1.7 (95% CI1.3-2.4, p < 0.001) compared to the normal BMI group.CONCLUSIONS:
Medical ward patients with severe obesity have a lower risk for mortality compared to patients with normal BMI. However, this does not apply during COVID-19, where obesity was a leading risk factor for mortality in the medical wards. It is important for the internal medicine physician to understand the intricacies of the association between obesity and medical ward mortality.Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Body Mass Index
/
Hospital Mortality
/
SARS-CoV-2
/
COVID-19
/
Hospitalization
/
Obesity
Type of study:
Cohort study
/
Experimental Studies
/
Observational study
/
Prognostic study
/
Randomized controlled trials
Limits:
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Country/Region as subject:
North America
Language:
English
Journal:
BMC Endocr Disord
Year:
2022
Document Type:
Article
Affiliation country:
S12902-021-00912-5
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