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Severe COVID-19 and Multisystem Inflammatory Syndrome in Children in Children and Adolescents.
Blatz, Allison M; Randolph, Adrienne G.
  • Blatz AM; Department of Pediatrics, Division of Infectious Diseases, Children's Hospital of Philadelphia, 3401 Civic Center Boulevard, Philadelphia, PA 19104, USA.
  • Randolph AG; Department of Anesthesiology, Critical Care and Pain Medicine, Division of Critical Care, Boston Children's Hospital, 300 Longwood Avenue, Bader 634, Boston, MA 02115, USA; Department of Anaesthesia and Pediatrics, Harvard Medical School, Boston, MA 02115, USA. Electronic address: adrienne.randolph@childrens.harvard.edu.
Crit Care Clin ; 38(3): 571-586, 2022 Jul.
Article in English | MEDLINE | ID: covidwho-1616399
ABSTRACT
Severe complications related to COVID-19 occur infrequently in children and adolescents. these life-threatening complications are mainly acute respiratory failure from acute COVID-19 and multisystem inflammatory syndrome in children (MIS-C). MIS-C is a postinfectious complication occurring approximately 3 to 6 weeks mostly after an asymptomatic or mild SARS-CoV-2 infection. For both types of complications, supportive ICU care is often required. For MIS-C critical illness, immunomodulation is prescribed to reverse hyperinflammation and its cardiac and other sequelae.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Type of study: Diagnostic study Topics: Long Covid Limits: Adolescent / Child / Humans Language: English Journal: Crit Care Clin Journal subject: Critical Care Year: 2022 Document Type: Article Affiliation country: J.ccc.2022.01.005

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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Type of study: Diagnostic study Topics: Long Covid Limits: Adolescent / Child / Humans Language: English Journal: Crit Care Clin Journal subject: Critical Care Year: 2022 Document Type: Article Affiliation country: J.ccc.2022.01.005